Clinical trial · Observational
Retrospective Analysis of Clinical and CT Features to Predict Spread Through Air Space in Stage IA Lung Adenocarcinoma
Clinical and Imaging Features Were Used to Predict the Occurrence of Spread Through Air Space in Stage IA Lung Adenocarcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to provide a basis for the selection of surgical methods for patients with stage IA lung adenocarcinoma. Air cavity dissemination is a poor prognostic factor for patients with stage IA lung adenocarcinoma. We retrospectively collected clinical and imaging data of stage IA lung adenocarcinoma patients. Independent risk factors associated with spread through air space in stage IA lung adenocarcinoma patients were analyzed, so as to predict the occurrence of spread through air space and provide basis for the selection of surgical methods
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Clinical Features | — | UNRESOLVED | — |
| Spread Through Air Space | — | UNRESOLVED | — |
| Stage IA Adenocarcinoma of Lung | Lung Adenocarcinoma | CURATED_BROADER | 0.78 |
| Tomography, X-Ray Computed | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- spread through air space positive group
- description
- The patients in this group were stage IA lung adenocarcinoma patients who met the inclusion and exclusion criteria, and the postoperative pathological results indicated the presence of spread through air space
- label
- spread through air space negative group
- description
- The patients in this group were stage IA lung adenocarcinoma patients who met the inclusion and exclusion criteria, and the postoperative pathological results showed no spread through air space
Primary outcomes (1)
- measure
- Accuracy of Predicting Spread Through Air Spaces (STAS) in Stage IA Lung Adenocarcinoma Using Clinical and Imaging Features
- timeFrame
- Preoperative clinical and imaging data collected within 2 weeks prior to surgery, retrospectively analyzed from patients who underwent surgery within the past 3 years
- description
- This outcome measure assesses the accuracy of using preoperative clinical and CT imaging features to predict the presence of spread through air spaces (STAS) in patients with stage IA lung adenocarcinoma.Measure: Area Under the ROC Curve (AUC), sensitivity, and specificity for the prediction model.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Preoperative CT images reported that the maximum diameter of pulmonary nodules was less than 3 cm All subjects provided CT imaging obtained from Yunnan Cancer Hospital within a 2-week period prior to surgery Postoperative pathological diagnosis of invasive lung adenocarcinoma Remote metastasis was excluded by preoperative imaging (CT, PET-CT, ultrasound, etc.) Age ≥ 18 years Exclusion Criteria: Incomplete collection of medical records, imaging data, or hematology data Preoperative complications of other malignant tumors Unclear correspondence between postoperative pathological report and preoperative CT nodule location Images do not meet analysis conditions due to pulmonary infection or large respiratory motion artifacts Postoperative pathology revealed two or more nodules classified as infiltrating adenocarcinoma Prior lung surgery or preoperative neoadjuvant therapy
References
Publications (0)
Data not yet available