Clinical trial · Observational
Liver Cancer Prognosis Investigation Study
Liver CAncer PRognosis InvEstigation Study (Liver-CARE)
NCT06623734CI-TRIAL-00086852not yet recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This prospective cohort study is designed to explore the role of environmental, clinical, and genetic risk factors in the progression and prognosis of primary liver cancer (PLC). We will recruit 5000 patients with newly diagnosed, previously untreated PLC. The eligible patients will be asked to complete a baseline survey at the time of initial admission and be followed up every 3 to 6 months after discharge.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Liver Neoplasms | Liver Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Death
- timeFrame
- Up to 20 years
- description
- The primary endpoint of this study is all-cause mortality and liver caner-specific mortality. The exact death time and the cause of death of each participant will be checked in the government medical records system.
Secondary outcomes (9)
- measure
- Recurrence (intrahepatic and extrahepatic)
- timeFrame
- From date of diagnosis until the date of cancer recurrence or date of death from any cause, whichever came first, assessed up to 20 years
- description
- Time of recurrence will be obtained by telephone interview or medical treatment records
- measure
- Newly Emerging Diseases
- timeFrame
- From date of diagnosis until the date of newly emerging diseases or date of death from any cause, whichever came first, assessed up to 20 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18-80 years, * Diagnosed with primary liver cancer (ICD-10: C22) (Referring to the diagnostic criteria in the "Primary Liver Cancer Diagnosis and Treatment Guidelines (2024 Edition)" and the "2024 CSCO Guidelines for the Diagnosis and Treatment of Biliary Malignancies), * Have not received any anti-tumor treatment (e.g., surgery, ablation, interventional therapy, radiotherapy, chemotherapy, targeted therapy, immunotherapy, etc), * Signed informed consent. Exclusion Criteria: * Have a history of other malignant tumors, * Have a history of other serious chronic diseases (e.g., heart failure, liver failure, kidney failure, etc.), * Expected survival time is no more than 3 months, * Severe physical or mental disability.
References
Publications (0)
Data not yet available
No reference posted for this study.