Clinical trial · Interventional
eSense-Cancer: Adapting an Online Intervention for Sexual Health Concerns to Gynecologic Cancer
NCT06619769CI-TRIAL-00095779eSense-CancerrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Sexual health is a vital component of gynecologic cancer treatment and survivorship. Unfortunately, most gynecologic cancer survivors lack sufficient information about the impact of cancer on sexual health and treatment opportunities. This research aims to assess how well an adapted online health intervention meets the sexual health needs of gynecologic cancer survivors and to test the efficacy of the new platform. If successful, eSense-Cancer may increase access to treatment for gynecologic cancer survivors, including those living in remote areas or facing other accessibility barriers. It may also fill healthcare gaps for survivors of varying ethnicity, sexual orientation, socioeconomic status, and gender.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gynecologic Cancers | Malignant Female Reproductive System Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Behavioral: eSense-Cancer MBT: an online cognitive-behavioural therapy based intervention for sexual health concerns after gynecologic cancer | Behavioral | — | UNRESOLVED |
| eSense-Cancer CBT: an online cognitive-behavioural therapy based intervention for sexual health concerns after gynecologic cancer | Behavioral | — | UNRESOLVED |
| Navigator support for eSense-Cancer | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- type
- ACTIVE_COMPARATOR
- label
- CBT - Navigator
- description
- Participants will complete the CBT arm of eSense with support from a treatment "navigator"
- interventionNames
- Behavioral: eSense-Cancer CBT: an online cognitive-behavioural therapy based intervention for sexual health concerns after gynecologic cancer
- Behavioral: Navigator support for eSense-Cancer
- type
- ACTIVE_COMPARATOR
- label
- CBT - No navigator
- description
- Participants will complete the CBT arm of eSense without support from a treatment "navigator"
- interventionNames
- Behavioral: eSense-Cancer CBT: an online cognitive-behavioural therapy based intervention for sexual health concerns after gynecologic cancer
- type
- ACTIVE_COMPARATOR
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 19 Years
Show eligibility criteria text
Inclusion Criteria: * self-report a current or history of gynecologic cancer of any subtype * self-report symptoms of sexual difficulties and score of greater than 11 on the Female Sexual Distress Scale-Revised * are fluent in English (eSense content is delivered in English) * have reliable internet access and basic competency in using online platforms (individuals will self-report) * are available for 8 - 16 weeks and able to complete eSense modules and associated questionnaires * any gender Exclusion Criteria: * have visual impairments or disabilities interfering with reading and ability to interact with online materials * have poorly managed anxiety or mood disorder (assessed using the degree of life interference evaluation at screening) * individuals who are in active treatment for their cancer (including radiation, chemotherapy and any planned surgeries).
References
Publications (5)
- BACKGROUNDBarrett-Lennard GT. The Relationship Inventory: A Complete Resource and Guide.
- BACKGROUNDBaker TB, Gustafson DH, Shaw B, Hawkins R, Pingree S, Roberts L, Strecher V. Relevance of CONSORT reporting criteria for research on eHealth interventions. Patient Educ Couns. 2010 Dec;81 Suppl:S77-86. doi: 10.1016/j.pec.2010.07.040. Epub 2010 Sep 16. PMID 20843621
- BACKGROUNDDerogatis L, Clayton A, Lewis-D'Agostino D, Wunderlich G, Fu Y. Validation of the female sexual distress scale-revised for assessing distress in women with hypoactive sexual desire disorder. J Sex Med. 2008 Feb;5(2):357-64. doi: 10.1111/j.1743-6109.2007.00672.x. Epub 2007 Nov 27. PMID 18042215
- BACKGROUNDKazdin AE. Acceptability of alternative treatments for deviant child behavior. J Appl Behav Anal. 1980 Summer;13(2):259-73. doi: 10.1901/jaba.1980.13-259. PMID 7380752
- BACKGROUNDBrotto LA, Stephenson KR, Zippan N. Feasibility of an Online Mindfulness-Based Intervention for Women with Sexual Interest/Arousal Disorder. Mindfulness (N Y). 2022;13(3):647-659. doi: 10.1007/s12671-021-01820-4. Epub 2022 Jan 4. PMID 35035598