Clinical trial · Observational
The Role of CircDENND4C in Epithelial Ovarian Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
circular RNAs (circRNAs), a newly discovered type of endogenous noncoding RNAs \[8\], are involved in the regulation of various biological functions. They act by sponging off certain microRNAs (miRNAs) and play a role in the pathogenesis of many diseases, including cancers \[9-11\]. In addition, circRNAs are not com- monly degraded by RNA enzymes present in body flu- ids \[8\], and most of them possess expression specificity at the tissue, cell, and developmental stage level \[12,13\]. Thus, they can be ideal clinica
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- role of circDENND4c in the diagnosis of ovarian cancer
- timeFrame
- baseline
- description
- by quality real time PCR we use the circDENND4c as a tumour marker for ovarian cancer
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: \- patients at South Egypt Cancer institute and Recently diagnosed ovarian cancer patients 2. Patients not went to surgery. Exclusion Criteria: * . Patients receive any anti-cancer therapy. 2. Patients diagnosed with other concomitante cancer or chronic disease
References
Publications (0)
Data not yet available