Clinical trial · Observational
Development of Tumor Organoids From Undifferentiated Primary Carcinomas to Guide Therapeutic Decisions
NCT06612827CI-TRIAL-00099624OCAPIrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study is based on the constitution of a collection of tumor and blood samples for the development of tumoroid for functional tests to predict clinical response to treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Undifferentiated Carcinoma | Undifferentiated Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| organoid etablishment | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Blood and tumor collection
- description
- Blood and tumor collection before treatment initiation
- interventionNames
- Other: organoid etablishment
Primary outcomes (1)
- measure
- Rate of establishment of exploitable tumor organoids
- timeFrame
- through study completion, an average of 3 years
- description
- Rate of establishment usable tumor organoids for predictive tests of response to treatment.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with undifferentiated primary carcinoma (UPC) with histological and immunohistochemical evidence, validated in a local and/or national UPC multidisciplinary consultation * Patient with indication for systemic 1st-line treatment at the time of inclusion. Treatment may already have begun at the time of inclusion, but within the limit of 2 treatment cycles administered. * Patient with life expectancy greater than 3 months * Patient of legal age * Patient affiliated to a social security scheme * Signature of informed consent prior to any specific study procedure Exclusion Criteria: * Persons deprived of their liberty or under guardianship (including curatorship) * Pregnant or breast-feeding patient
References
Publications (0)
Data not yet available
No reference posted for this study.