Clinical trial · Observational
Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules
NCT06610604CI-TRIAL-00081009recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this observational research is to evaluate and compare the health-related quality of life and emotional well-being of patients with thyroid nodules before and after treatment. This is a data collection study by allowing investigators to access information generated before and after treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| thermal ablation | Procedure | — | UNRESOLVED |
| thyroidectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- thyroidectomy
- description
- patients with thyroid nodules who undergo surgical resection
- interventionNames
- Procedure: thyroidectomy
- label
- thermal ablation
- description
- patients with thyroid nodules who undergo thermal ablation
- interventionNames
- Procedure: thermal ablation
Primary outcomes (4)
- measure
- The Thyroid Cancer-Specific Quality of Life Questionnaire to assess the thyroid-specific quality of life
- timeFrame
- before treatment and 1month, 6months, and 12 months after treatment
- description
- The Thyroid Cancer-Specific Quality of Life Questionnaire (THYCA-QoL), as a methodologically developed questionnaire, was used to assess thyroid-specific symptoms in thyroid cancer survivors. The questionnaire consists of seven symptom scales (neuromuscular, voice, concentration, sympathetic, throat/mouth, psychological and sensory problems) and six single items (problems with scar, felt chilly, tingling hands/feet, gained weight, headache, less interest in sex), with a time frame of the previous week (except for less interest in sex item, which is four weeks), and each item is scored on a four-point response scale ranging from 1, "not at all", to 4, "very much". Scores were linearly transformed to a 0-100 scale. A higher score on this scale means more symptoms and complaints.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Clinical diagnosis of benign thyroid nodules or papillary thyroid carcinoma ; * underwent microwave ablation or thyroidectomy; * ability to understand and cooperate with the survey Exclusion Criteria: * serious primary diseases in the liver, kidney, hematopoietic, or endocrine systems； * a history of mental illness, personality disorders, cognitive impairments, or organic brain disease
References
Publications (0)
Data not yet available
No reference posted for this study.