Clinical trial · Interventional
NIFR Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose SWIG Technique
Near-infrared Fluorescence Image-guided Surgery for Malignant Soft Tissue Tumor With Low-dose Second Window Indocyanine Green Technique: a Multicenter Randomized Controlled Trial
NCT06610071CI-TRIAL-00080994NIFR;SWIGnot yet recruitingPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research study will evaluate how near-infrared fluorescence (NIRF) imaging with low-dose second window indocyanine green (ICG) can assist in the radical resection and pathologic diagnosis of malignant soft tissue sarcoma, such as dermatofibrosarcoma protuberans (DFSP) and skin squamous cell carcinoma (sSCC) during surgery.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Dermatofibrosarcoma Protuberans (DFSP) | Dermatofibrosarcoma Protuberans | ONTOLOGY_EXACT | 0.85 |
| Skin Squamous Cell Carcinoma | Skin Squamous Cell Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ICG administration | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (6)
- type
- EXPERIMENTAL
- label
- Patients with DFSP in the first experimental group
- description
- The ICG was injected intravenously 24 hours before surgery at a dose of 0.25 mg/kg in the first experimental group.
- interventionNames
- Drug: ICG administration
- type
- EXPERIMENTAL
- label
- Patients with DFSP in the second experimental group
- description
- The ICG was injected intravenously 24 hours before surgery at a dose of 25 mg/patient in the second experimental group.
- interventionNames
- Drug: ICG administration
- type
- NO_INTERVENTION
- label
- Patients with DFSP in the control group
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Patients with DFSPs or sSCC in heads, extremities or trunk Exclusion Criteria: * seafood/iodine allergy * hyperthyroidism * pregnancy * myasthenia gravis * acute severe hypertension
References
Publications (0)
Data not yet available
No reference posted for this study.