Clinical trial · Observational
Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery
Evaluation of the Relationship Between Preoperative Prognostic Nutritional Index and Postoperative Delirium in Gastrointestinal Cancer Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aim: We aimed to show the relationship between preoperative prognostic nutritional index and postoperative delirium in patients who had undergone gastrointestinal cancer surgery. Materials and Methods: Our study is a single-center, prospective, observational study. Routine preoperative anesthesia evaluation of all patients was performed and patient's age, sex, ASA physical score, body mass index (BMI), existing comorbid diseases, level of education, smoking status, cancer diagnosis, chemotherapy and radiotherapy history, type of surgery, past invasive interventions, concentration of hemoglobin and albumin, lymphocyte count, liver and kidney function tests were recorded. PNI score was calculated with the preoperative measurements. With the calculated PNI score, nutritional status was defined as normal (PNI ≥50), mild malnutrition (PNI 45-50), moderate-severe malnutrition (PNI 40-45), and severe (PNI \<40) accordingly. The patients were then evaluated for the presence of delirium using the Confusion Assessment Method (CAM) for 3 days postoperatively.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Confusion Postoperative | — | UNRESOLVED | — |
| Delirium | — | UNRESOLVED | — |
| Gastrointestinal Cancer | Malignant Digestive System Neoplasm | ALIAS | 0.90 |
| Nutritional Deficiency | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| prognostic nutritional index | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Delirium Group
- description
- group that developed delirium within 3 days postoperatively
- interventionNames
- Diagnostic Test: prognostic nutritional index
- label
- Non Delirium Group
- description
- group that did not develop delirium within 3 days postoperatively
- interventionNames
- Diagnostic Test: prognostic nutritional index
Primary outcomes (1)
- measure
- Evaluation of the development of delirium
- timeFrame
- 15 October 2021-20 May 2022
- description
- Evaluation of whether delirium develops in postoperative patients within the first 3 days using the Confusion Assessment Method (CAM)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged 18 and over * Patients who will undergo gastrointestinal cancer surgery * Able to give voluntary consent * ASA I-IV patients Exclusion Criteria: * Under 18 years old * Those who do not agree to be included in the study * Unconscious * Hearing, sight and speech impaired * Chronic alcohol user * Patients with cognitive or psychiatric disorders such as known dementia, Parkinson's, Alzheimer's * Patients who need postoperative mechanical ventilation support
References
Publications (1)
- BACKGROUNDLiu H, Dai M, Guan H, Gao X, Zhou Y, Sun X, Zhou J, Hu X, Li X, Song Y, Han Y, Cao J. Preoperative Prognostic Nutritional Index Value is Related to Postoperative Delirium in Elderly Patients After Noncardiac Surgery: A Retrospective Cohort Study. Risk Manag Healthc Policy. 2021 Jan 6;14:1-8. doi: 10.2147/RMHP.S280567. eCollection 2021. PMID 33442311