Clinical trial · Observational
Postoperative Complications Following Skull Base Tumor Resection
Postoperative Complications Following Skull Base Tumor Resection: an Observational Study
NCT06587906CI-TRIAL-00086047recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The skull base tumor is located in the deep intracranial layer and is closely related to the brain stem and intracranial nerves. The incidence of postoperative complications after skull base tumor resection is high. Therefore, the perioperative management of skull base tumor resection is challenging.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Postoperative Complications | — | UNRESOLVED | — |
| Skull Base Tumor | Skull Base Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Pulmonary ultrasound examination | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- The incidence of postoperative pulmonary complications
- timeFrame
- Postoperative 7 days
- description
- The primary outcome was the incidence of a composite endpoint of postoperative pulmonary complicationswithin 7 days after surgery. Postoperative pulmonary complications was considered to have occurred if at least one postoperative pulmonary event was observed, such as the pneumonia, pleural effusion, respiratory failure, hypoxemia, pneumothorax, atelectasis of the lung, bronchospasm..Ultrasound scans were performed at 20 min before starting mechanical ventilation of the lungs (before intubation) and performed at 20 min after surgery (after extubation)
Secondary outcomes (5)
- measure
- The incidence of postoperative deep venous thrombosis
- timeFrame
- Postoperative 7 days
- description
- Lower extremity venous ultrasound, preoperative and postoperative coagulation related values, blood routine, etc
- measure
- Cardiac injury
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 and above * American Society of Anesthesiologists physical status I to III * Undergoing elective resection of skull base tumors * Obtaining written informed consent Exclusion Criteria: * Heart failure, myocarditis, pericarditis, and cardiomyopathy * Myocardial ischemia less than 6 months old * Severe arrhythmia * Severe bradycardia (heart rate below 50 beats per minute) * Unable to complete preoperative cardiac assessment * Severe liver dysfunction (Child Pugh C-grade) * Severe lung diseases
References
Publications (0)
Data not yet available
No reference posted for this study.