Clinical trial · Observational
Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
Effect of Cancer Treatment on Testicular Function and Semen Quality in Male Childhood and Adolescent Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer treatment can affect the testicular function, including sperm and hormonal functions. The aim of this study is to assess the testicular function and semen quality in young men who recover from childhood and adolescent cancer in Hong Kong. This can provide more information for pre-treatment counselling as well as improve post treatment survivorship care. The testicular function will be compared to aged-matched controls from men attending the Family Planning Association for premarital check-up.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer, Treatment-Related | Malignant Neoplasm | ALIAS | 0.85 |
| Late Effect | — | UNRESOLVED | — |
| Semen Analysis | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hormonal profile | Other | — | UNRESOLVED |
| Questionnaire | Other | — | UNRESOLVED |
| Semen analysis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Male childhood and adolescent cancer survivors
- description
- Male childhood and adolescent cancer survivors
- interventionNames
- Other: Hormonal profile
- Other: Semen analysis
- Other: Questionnaire
- label
- Controls
- description
- Aged-matched controls from men attending the Family Planning Association for premarital check-up
- interventionNames
- Other: Hormonal profile
- Other: Semen analysis
- Other: Questionnaire
Primary outcomes (1)
- measure
- Sperm concentration
- timeFrame
- up to 3 months
- description
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * Men who have received chemotherapy and/ or radiotherapy for cancer diagnosed when they were \< 18 years old. * \> 18 years old to 50 years old * Cancer in remission for at least 2 years Exclusion Criteria: * Unable to ejaculate by masturbation to provide semen samples * Cryptorchidism, testicular cancer, history of vasectomy * On testosterone replacement therapy * Refusal to join the study
References
Publications (0)
Data not yet available