Clinical trial · Interventional
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery: A Randomized Clinical Trial
NCT06574152CI-TRIAL-00122213recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the effect of Photobiomodulation (PBM) in postoperative pain after endodontic microsurgery (EMS) in patients from the University of Texas Health Science Center at Houston, School of Dentistry Graduate Endodontic Clinic and to assess the soft tissue healing of the vertical releasing incision (VRI) after PBM
Conditions
Conditions (7)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Apical Cyst | — | UNRESOLVED | — |
| Apical Granuloma | — | UNRESOLVED | — |
| Apical Periodontitis | — | UNRESOLVED | — |
| Endodontically Treated Teeth | — | UNRESOLVED | — |
| Endodontic Disease | — | UNRESOLVED | — |
| Periradicular Disease | — | UNRESOLVED | — |
| Previous Endodontic Treatment | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| EMS | Device | — | UNRESOLVED |
| PBM sham treatment | Device | — | UNRESOLVED |
| PBM treatment | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- EMS and PBM treatment 25s group
- description
- Photobiomodulation (PBM) therapy will be performed using a 660 nm diode laser (SiroLaser Advance Plus, Dentsply Sirona Inc, Charlotte, North Carolina, USA) following the outline of the incision flap in a contact mode. Each site will be irradiated for 25 seconds with an energy density of 10 J/cm2 (irradiation mode).
- interventionNames
- Device: PBM treatment
- Device: EMS
- type
- SHAM_COMPARATOR
- label
- EMS and PBM sham treatment
- description
- The laser tip will be placed following the outline of the incision flap in a contact mode but without activating it (no irradiation).
- interventionNames
- Device: PBM sham treatment
- Device: EMS
- type
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * American Society of Anesthesiologists (ASA) I or II. * At least one tooth will receive EMS. * Flap design that includes at least one VRI (triangular, rectangular, papilla base or submarginal rectangular). Exclusion Criteria: * ASA III or IV. * Current heavy smokers (\>10 cigarettes/day) * Uncontrolled diabetes (HbA1c ≥ 7%) or other uncontrolled systemic diseases that may comprise healing, such as vitamin C deficiency, neutrophil deficiencies, immunodeficiency syndromes, or leukemia. * Surgical access on the palatal surface. * Acute swelling or abscess present on the day of the surgery. * Any event or condition that would make continued participation in the study not in the best interest of the subject, as determined by the investigator. * Pregnancy. * Development of any medical condition that might affect the treatment and clinical outcomes, as determined by the investigator. * Initiation of any treatment or exposure that might affect therapy's healing, as determined by the investigator.
References
Publications (0)
Data not yet available
No reference posted for this study.