Clinical trial · Interventional
Oral Protein Supplements for Nutritional and Quality of Life Improvement After Pancreatic Resection in Elderly Patients
Oral Protein Supplements Might Improve Nutritional Status and Quality of Life in Elderly Patients After Standard Pancreatic Resection
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates the effects of oral protein supplements on the nutritional status and quality of life in elderly patients following standard pancreatic resection. The research aims to determine whether these supplements can improve protein intake and contribute to better skeletal muscle mass, which is critical for recovery and overall health. The study hypothesizes that higher compliance with protein supplementation will be positively correlated with increased protein intake and improved muscle mass index, potentially leading to enhanced postoperative outcomes in this patient population.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cholangiocarcinoma | Cholangiocarcinoma | ONTOLOGY_EXACT | 0.98 |
| Intraductal Papillary Mucinous Neoplasm | Pancreatic Intraductal Papillary Mucinous Neoplasm | ALIAS | 0.90 |
| Neuroendocrine Tumor | Neuroendocrine Tumor | ONTOLOGY_EXACT | 0.90 |
| Pancreatic Cancer | Malignant Pancreatic Neoplasm | CURATED_EXACT | 0.92 |
| Solid Pseudopapillary Tumor | Solid Pseudopapillary Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| oral protein supplements | Dietary Supplement | — | UNRESOLVED |
| placebo | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Protein Supplement group
- description
- This group received a daily oral protein supplement providing 18g of protein. The supplement was administered postoperatively and continued throughout the study period to evaluate its impact on nutritional status, quality of life, muscle mass, muscle strength, and gait speed.
- interventionNames
- Dietary Supplement: oral protein supplements
- type
- PLACEBO_COMPARATOR
- label
- Placebo group
- description
- This group received a placebo that contained carbohydrates instead of protein. The placebo was identical in appearance and taste to the protein supplement, ensuring the double-blind nature of the study. This arm was used to compare the effects of the protein supplement on the same outcomes.
- interventionNames
- Genetic: placebo
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Patients aged 65 years or older who were diagnosed with and underwent surgery for one of the following cancers: 1. pancreatic cancer 2. cholangiocarcinoma 3. intraductal papillary mucinous neoplasm 4. neuroendocrine tumor 5. solid pseudopapillary tumor. Exclusion Criteria: * Patients were excluded from the study if they met any of the following criteria: 1. Patients who were assessed as severely malnourished before surgery (PG-SGA grade C); 2. Patients with an estimated glomerular filtration rate (eGFR) of less than 60 mL/min, or those diagnosed with chronic kidney disease and a history of related treatment; 3. Patients with a body mass index (BMI) of 30 kg/m² or higher; 4. Patients with ascites or edema severe enough to affect weight evaluation; 5. Patients whose bioelectrical impedance analysis (BIA) could not be measured due to the use of pacemakers or implants; 6. Patients whom the researcher deemed unable to participate in the study for psychological or cognitive reasons; 7. Patients who did not provide consent for participation in this study.
References
Publications (0)
Data not yet available