Clinical trial · Interventional
Implementing Good Nutrition to Improve, Transform, and Enhance (IGNITE) Firefighters' Health
NCT06567561CI-TRIAL-00107624completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Investigators hope to learn about potential dietary intervention strategies (specifically a whole-food, plant-based diet) that may help lower cancer markers in firefighters.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Immune Function | — | UNRESOLVED | — |
| Inflammation | — | UNRESOLVED | — |
| Microbiome | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Usual Firehouse Diet | Behavioral | — | UNRESOLVED |
| Whole Foods Plant-Based Diet | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Whole Food Plant-Based Diet
- description
- Participants will be asked to consume and predominantly vegan, whole-foods diet, with the addition of fish, eggs, and fermented dairy.
- interventionNames
- Behavioral: Whole Foods Plant-Based Diet
- type
- ACTIVE_COMPARATOR
- label
- Usual Firehouse Diet
- description
- Participants will be asked to consume their usual firehouse meals.
- interventionNames
- Behavioral: Usual Firehouse Diet
Primary outcomes (1)
- measure
- Difference in IL-6
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18+ * Active SF firefighter * Willing to consume a plant-based diet (vegetables, fruit, whole grains, legumes, etc.) * Willing to complete 4 clinic visits Exclusion Criteria: * Weight \< 110 lb * BMI \>= 40 * Self-reported uncontrolled hypercholesterolemia, hypertension or diabetes * Pregnant, lactating, or planning to become pregnant during the course of the study. * Use of any of the following drugs/supplements within the last 2 months: * systemic antibiotics, antifungals, antivirals, or antiparasitics (intravenous, intramuscular, or oral); * corticosteroids (intravenous, intramuscular, oral, nasal or inhaled); * cytokines; * methotrexate or immunosuppressive cytotoxic agents. * Chronic, clinically significant, or unstable (unresolved, requiring ongoing changes to medical management or medication) pulmonary, cardiovascular, gastrointestinal, hepatic or renal functional abnormality, as determined by medical history, Type 1 diabetes, dialysis * History of active cancer in the past 3 years except for squamous or basal cell carcinomas of the skin that have been medically managed by local excision * Unstable dietary history as defined by major changes in diet during the previous month, where the subject has eliminated or significantly increased a major food group in the diet. * Recent history of chronic excessive alcohol consumption defined as more than five 1.5-ounce servings of 80 proof distilled spirits, five 12-ounce servings of beer or five 5-ounce servings of wine per day; or \> 14 drinks/week. * Any confirmed or suspected condition/state of immunosuppression or immunodeficiency (primary or acquired) including HIV infection, multiple sclerosis, and Graves' disease. * Surgery of the GI tract, with the exception of cholecystectomy and appendectomy, in the past five years. Any major bowel resection at any time. * Regular/frequent use of smoking or chewing tobacco, e-cigarettes, cigars or other nicotine-containing products * Regular use of prescription opiate pain medication
References
Publications (0)
Data not yet available
No reference posted for this study.