Clinical trial · Interventional
EB-OCT Biopsy Guidance of Lung Cancer
Develop a High-resolution EB-OCT Platform to Visualize, Guide, Evaluate, and Increase the Accuracy of Lung Cancer Diagnosis in Human Subjects
NCT06556680CI-TRIAL-00080244not yet recruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Our objective is to develop, test, and validate a clinically robust polarization-sensitive optical coherence tomography (PS-OCT) biopsy guidance and diagnosis platform that is compatible with standard bronchoscopy techniques.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Optical coherence tomography | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control Arm
- description
- In the control arm, patients will only receive their regular scheduled bronchoscopy for biopsy.
- type
- EXPERIMENTAL
- label
- OCT Imaging Arm
- description
- In the OCT-imaging arm, OCT images will be obtained and and used for biopsy guidance.
- interventionNames
- Device: Optical coherence tomography
Primary outcomes (1)
- measure
- Diagnostic yield of bronchial biopsy
- timeFrame
- 2 years
- description
- EB-OCT guided bronchial biopsy changes the diagnostic yield when compared to traditional biopsy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
Show eligibility criteria text
Inclusion Criteria: * Patients undergoing elective lung biopsy for known or suspected malignancy in the lung * Patients must be over the age of 21 * Patient must be able to give informed consent * Negative pregnancy test for all females of childbearing potential who are sexually active and not using contraception, are seeking to become pregnant, or are nursing Exclusion Criteria: * Patients who are pregnant * The patient does not meet the requirements to undergo clinical bronchoscopy, as determined by the treating physician.
References
Publications (0)
Data not yet available
No reference posted for this study.