Clinical trial · Observational
The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery
The Outcomes of Simultaneous Resection for Colorectal Cancer Liver Metastases by Laparoscopic Hybrid Surgery Versus Totally Open Surgery: a Prospective Cohort Study
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with resectable SCRLM. Simultaneous resection of colorectal cancer liver metastases by totally open surgery (TOS) has been widely used. However, we propose that laparoscopic hybrid surgery (LHS) may have better short and long-term outcomes. This study aimed to compare the safety, short-term, and long-term efficacy of LHS versus TOS for patients with resectable SCRLMs.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Resectable Simultaneous Colorectal Cancer Liver Metastasis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laparoscopic hybrid surgery (LHS) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- laparoscopic hybrid surgery (LHS) cohort
- description
- Routine colorectal surgery is performed first, followed by liver surgery. The LHS cohort first performed the laparoscopic exploration of the entire abdominal-pelvic cavity to determine the resectability of the primary and metastatic lesions. After the blood vessel detachment and bowel detachment, the distal bowel of the tumor was severed and the pneumoperitoneum was closed. The liver metastases were then removed in both cohorts by open resection through the right subcostal incision.
- interventionNames
- Procedure: laparoscopic hybrid surgery (LHS)
- label
- totally open surgery (TOS) cohort
- description
- Routine colorectal surgery is performed first, followed by liver surgery. The blood vessel detachment, bowel detachment, the distal bowel of the tumor in the TOS cohort were accomplished by open surgery through the mid-abdominal incision approach. The liver metastases were then removed in both cohorts by open resection through the right subcostal incision.
Primary outcomes (5)
- measure
- short-term outcome: Operative time
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Liver metastasis was detected while the colorectal cancer was diagnosed. * Both the primary lesions and liver metastases were confirmed by postoperative pathological examination. * Clinical data is complete. Exclusion Criteria: * Patients with unresectable extrahepatic metastases. * Patients with other malignant tumor diseases that have not been cured. * Clinical and pathological data were missed or incomplete follow-up data.
References
Publications (0)
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