Clinical trial · Interventional
Comparison of Method for Skin Closure in Colorectal Cancer.
A Study on Comparison of Postoperative Outcome Between Conventional Skin Stapling and Tissue Adhesive (2-octyl Cyanoacrylate) for Skin Closure in Colorectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Compared to tissue adhesives and skin stapling devices, tissue adhesives are reported to have advantages in terms of wound infection and cost competitiveness. However, there have been no prospective randomized studies focusing on wound infection rates and cost competitiveness between skin stapling devices and tissue adhesives in colorectal cancer surgery. In colon cancer surgery, it is still unclear which skin suturing method has advantages such as lower postoperative wound infection rate and price competitiveness. The purpose of this study is to compare clinical outcomes, including wound infection rates and cost-effectiveness, between two different wound closure methods for colorectal cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Surgical Site Infection | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| skin bond | Device | — | UNRESOLVED |
| skin stapler | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Skin adhesive bond
- description
- a group which skin closure was performed using Leukosan Adhesive skin bond
- interventionNames
- Device: skin bond
- type
- ACTIVE_COMPARATOR
- label
- skin stapler
- description
- a group which skin closure was performed using skin stapler
- interventionNames
- Device: skin stapler
Primary outcomes (1)
- measure
- incidence of surgical site infection within 30 days after surgery
- timeFrame
- through study completion, an average of 1 year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * underwent elective colorectal surgery * aged 19 to 80 years * ASA (American Society of Anesthesiologists) score: 1, 2 * surgical approach such as laparoscopic or Robotic Xi platform Exclusion Criteria: * ASA score above 3 * Aged over 80 years * underwent combined surgery for other organ resection * uncontrolled DM
References
Publications (1)
- RESULTLee CS, Han SR, Kye BH, Bae JH, Koh W, Lee IK, Lee DS, Lee YS. Surgical skin adhesive bond is safe and feasible wound closure method to reduce surgical site infection following minimally invasive colorectal cancer surgery. Ann Surg Treat Res. 2020 Sep;99(3):146-152. doi: 10.4174/astr.2020.99.3.146. Epub 2020 Aug 27. PMID 32908846