Clinical trial · Observational
A Study for Dynamic Prediction Model of Breast Cancer Bone Metastases
A Clinical Study to Establish a Dynamic Prediction Model for Bone Metastases Based on Breast Cancer Real-world Data
NCT06544668CI-TRIAL-00079665unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to identify the risk factors of bone metastasis in breast cancer patients so as to develop a dynamic prediction model using real world clinical data. The multicenter data will be retrospectively collected, and the clinical characteristics related to bone metastasis will be analyzed.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Metastases | Breast Neoplasm | PROBABILISTIC | 0.70 |
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Breast cancer patients with bone metastasis | Other | — | UNRESOLVED |
| Breast cancer patients without bone metastasis | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Breast cancer patients with bone metastasis
- interventionNames
- Other: Breast cancer patients with bone metastasis
- label
- Breast cancer patients without bone metastasis
- interventionNames
- Other: Breast cancer patients without bone metastasis
Primary outcomes (1)
- measure
- To identify the risk factors and develop a prediction model for bone metastasis in breast cancer patients
- timeFrame
- 60 months
- description
- The correlation between clinical characteristics and bone metastasis, and the accuracy of prediction model
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 20 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients diagnosed with breast cancer by histopathology; 2. Age between 20 and 70 years old; 3. The first diagnosis time is between 2010 and 2020; 4. Complete diagnosis and treatment information, including basic information, breast cancer diagnosis, surgery, recurrence diagnosis data (including the diagnosis of the metastasis sites), anti-tumor treatment data, bone health and bone metastasis-related diagnosis and treatment data, etc.; 5. Sufficient available follow-up information. Exclusion Criteria: 1. Missing important basic information (including initial and recurrent pathology, stage, pathological grade and time, surgery time, and drug treatment); 2. With distant metastasis at the initial diagnosis; 3. Patients with autoimmune diseases or aggressive viral infections (such as HIV or hepatitis); 4. Other malignant tumors; 5. Unclear information about distant metastasis.
References
Publications (0)
Data not yet available
No reference posted for this study.