Clinical trial · Interventional
Nasoseptal Double Flap Versus Rescue Flap in Endoscopic Transsphenoidal Pituitary Surgery
NCT06526481CI-TRIAL-00079700completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This paper investigates the outcomes of two surgical techniques-nasoseptal double flap and nasoseptal rescue flap-used in endoscopic transsphenoidal surgery for pituitary tumors. The nasoseptal flap technique has significantly reduced the incidence of postoperative Cerebrospinal Fluid (CSF) leaks but can cause nasal morbidity.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pituitary Adenoma | Pituitary Neuroendocrine Tumor | ALIAS | 0.90 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic Transsphenoidal pituitary surgery : Double Nasoseptal Flap Technique | Procedure | — | UNRESOLVED |
| Endoscopic Transsphenoidal pituitary surgery : Rescue Flap Technique | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Double nasoseptal flap
- description
- Nasoseptal double flap group: -On one side full sized nasoseptal flap will be elevated and a smaller sized nasoseptal flap will be elevated on the other side.
- interventionNames
- Procedure: Endoscopic Transsphenoidal pituitary surgery : Double Nasoseptal Flap Technique
- type
- EXPERIMENTAL
- label
- Rescue nasoseptal flap
- description
- Nasoseptal rescue flap group: \- A horizontal incision will be performed in the nasal septum in a posterior to anterior direction starting from the sphenoid ostium to a point opposite anterior end of the middle turbinate ( approximately up to one half of septum).
- interventionNames
- Procedure: Endoscopic Transsphenoidal pituitary surgery : Rescue Flap Technique
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * All consecutive patients with symptomatic pituitary macroadenoma * Tumor size ≥ 2 cm Exclusion Criteria: * -Absent sphenoid pneumatization. * Temporal or frontal extension. * Recurrent pituitary tumor after previous surgery. * Previous nasal surgery. * Associated nasal disease e.g. rhinosinusitis. * Unfit for general anesthesia. * Refusal of surgical intervention or signing consent.
References
Publications (0)
Data not yet available
No reference posted for this study.