Clinical trial · Observational

Gastric Cancer Complicated With Bleeding

Retrospective Study on Anti-cancer Therapy for Gastric Cancer Patients Complicated With Bleeding

NCT06522542CI-TRIAL-00079147unknownClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

To investigate the impact of bleeding on the survival and treatment-related adverse events (TRAEs) of gastric cancer patients.

Conditions

Conditions (1)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Gastric Cancer	Malignant Gastric Neoplasm	CURATED_BROADER	0.80

Interventions

Interventions (1)

Intervention	Type	Mapped drug	Match
systematic therapy	Drug	—	UNRESOLVED

Design

Arms and outcomes

Arms (2)

label
Test group
description
Gastirc cancer with bleeding at first diagnosis
interventionNames
1. Drug: systematic therapy
label
Control group
description
Gastirc cancer without bleeding at first diagnosis
interventionNames
1. Drug: systematic therapy

Primary outcomes (1)

measure
Overall survival (OS)
timeFrame
from date of the first cycle of systematic therapy to death from any cause，assessed up to 120 months
description
OS was defined as the time from the first cycle of systematic therapy to death from any cause.

Eligibility

Eligibility (as posted)

Sex: All
Minimum age: 18 Years

Show eligibility criteria text

Inclusion Criteria:

1. Patients older than 18 years;
2. A histologically confirmed diagnosis of advanced or metastatic gastric cancer;
3. The initial anticancer treatment was systematic therapy, including chemotherapy, targeted therapy or immune checkpoint inhibitor (ICI);
4. No history of gastrectomy before systematic therapy.

Exclusion Criteria:

1. Incompletable clinical data;
2. Siewert I type esophagus cancer.

References

Publications (1)

DERIVEDYao Y, Liu Z, Zhang H, Shi X, Huang F, Zhang Y, Chen L, Shi Y, Cao B. Feasibility of systemic therapy in unresectable gastric/gastroesophageal junction cancer with overt bleeding. Asia Pac J Oncol Nurs. 2025 Jul 7;12:100750. doi: 10.1016/j.apjon.2025.100750. eCollection 2025 Dec. PMID 40747247