Clinical trial · Observational
Rehabilitation With an Obturator in Maxillary Defects
Comparison of Quality of Life After Rehabilitation With an Obturator in Maxillary Defects Due to COVID-19 Associated Mucormycosis and Oral Cancer.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
During the COVID-19 pandemic, there was a lot of reporting of COVID-19-associated mucormycosis cases. Managing this condition posed a new challenge to clinicians. Management includes therapeutic drugs and aggressive surgical debridement. Due to the unpredictability of disease prognosis and the possible recurrence of the disease, rehabilitation with delayed surgical obturators is beneficial for patients. Hence, the current study aimed to evaluate the impact of delayed surgical obturators on quality of life of COVID-19-associated mucormycosis patients post-maxillectomies
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Mucormycosis | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Obturator Prosthetic Rehabilitation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Oral Neoplasm
- description
- Patients who underwent maxillectomy for oral neoplasms and subsequently received obturator prosthetic rehabilitation. Eligible patients had Brown Class IIa, IIb, or IIc maxillary defects. Patient records from the Prosthodontic Department were retrospectively reviewed. OHIP-14 scores were recorded at four assessment time points: after surgical removal of the maxillary defect and before obturator rehabilitation, after insertion of the delayed surgical obturator, after insertion of the transitional obturator, and after insertion of the definitive obturator. The Obturator Functioning Scale (OFS) was recorded only after prosthesis insertion and was therefore assessed at three time points: after the delayed surgical, transitional, and definitive obturators.
- interventionNames
- Other: Obturator Prosthetic Rehabilitation
- label
- COVID-19-Associated Mucormycosis (CAM)
- description
- Patients who underwent maxillectomy for COVID-19-associated mucormycosis (CAM) and subsequently received obturator prosthetic rehabilitation. Eligible patients had Brown Class IIa, IIb, or IIc maxillary defects. Patient records from the Prosthodontic Department were retrospectively reviewed. OHIP-14 scores were recorded at four assessment time points: after surgical removal of the maxillary defect and before obturator rehabilitation, after insertion of the delayed surgical obturator, after insertion of the transitional obturator, and after insertion of the definitive obturator. The Obturator Functioning Scale (OFS) was recorded only after prosthesis insertion and was therefore assessed at three time points: after the delayed surgical, transitional, and definitive obturators.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 25 Years
- Maximum age
- 70 Years
Show eligibility criteria text
* Inclusion criteria * Age ≥25 years * Dentulous or partially dentulous * Underwent maxillectomy for oral neoplasm or CAM * Brown Class Ila, Ilb, or Iic maxillary defect involving the palate, nasal mucosa, and/or •paranasal sinuses requiring obturator rehabilitation * Exclusion criteria * Brown Class I defect * Bilateral maxillectomy (Brown Class Ild) * Brown Class III-IV/extensive defects * Orbital involvement/orbital exenteration * Defects extending beyond Brown classification * Transfacial surgical approach * Concomitant mandibulectomy * Complete edentulism * Severe trismus preventing definitive prosthesis fabrication * Tumor at a distant body site * Refusal to participate
References
Publications (0)
Data not yet available