Clinical trial · Interventional
Pilonidal Sinus Disease
LASER ABLATION VERSUS KARYDAKIS TECHNIQUE IN THE TREATMENT OF PILONIDAL SINUS DISEASE: A COMPARATIVE STUDY
NCT06508086CI-TRIAL-00078908unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study is to compare the outcomes of Karydakis technique versus sinus tract ablation procedure using 1470 nm Diode laser for the treatment of pilonidal sinus and provide evidence-based guidance to select the most appropriate operative procedure.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pilonidal Sinus | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Karydakis technique in the treatment of pilonidal sinus | Procedure | — | UNRESOLVED |
| laser ablation technique in the treatment of pilonidal sinus | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- group (A) LASER ABLATION
- interventionNames
- Procedure: laser ablation technique in the treatment of pilonidal sinus
- type
- ACTIVE_COMPARATOR
- label
- group (B) KARYDAKIS TECHNIQUE
- interventionNames
- Procedure: Karydakis technique in the treatment of pilonidal sinus
Primary outcomes (1)
- measure
- recurrence rate in the treatment of pilonidal disease
- timeFrame
- 6 months after the operation
- description
- the patients undergo follow up at the outpatient clinic for manifestations of recurrence eg. discharge, multiple pits
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * All patients with a clinical diagnosis of symptomatic uncomplicated pilonidal sinus, males or females, any age will be included in our study. Exclusion Criteria: * Patients with pilonidal abscess and any associated acute condition. * Patients with hidradenitis suppurativa. * Refusal. * Unfit for surgery. * Recurrence.
References
Publications (3)
- BACKGROUNDGuner A, Cekic AB, Boz A, Turkyilmaz S, Kucuktulu U. A proposed staging system for chronic symptomatic pilonidal sinus disease and results in patients treated with stage-based approach. BMC Surg. 2016 Apr 16;16:18. doi: 10.1186/s12893-016-0134-5. PMID 27084534
- BACKGROUNDDoll D, Matevossian E, Wietelmann K, Evers T, Kriner M, Petersen S. Family history of pilonidal sinus predisposes to earlier onset of disease and a 50% long-term recurrence rate. Dis Colon Rectum. 2009 Sep;52(9):1610-5. doi: 10.1007/DCR.0b013e3181a87607. PMID 19690490
- BACKGROUNDDessily M, Charara F, Ralea S, Alle JL. Pilonidal sinus destruction with a radial laser probe: technique and first Belgian experience. Acta Chir Belg. 2017 Jun;117(3):164-168. doi: 10.1080/00015458.2016.1272285. Epub 2017 Jan 6. PMID 28056720