Clinical trial · Interventional
Cuff Shape and Postoperative Sore Throat in Breast Cancer Patients
Comparisons of Postoperative Sore Throat and Subglottic Airway Injury Between Endotracheal Tubes With Different Cuff Shapes in Breast Cancer Patients
NCT06505850CI-TRIAL-00084384completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aimed to evaluate the impact of endotracheal tube cuff shapes on the incidence and severity of postoperative sore throat
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Endotracheal Tube Cuff | — | UNRESOLVED | — |
| Postoperative Sore Throat | — | UNRESOLVED | — |
| Subglottic Airway Injury | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cylindrical-shaped cuff tracheal tube | Device | — | UNRESOLVED |
| Tapered-shaped cuff tracheal tube | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Tapered-shaped cuff ETT group
- description
- A tapered-shaped cuff tube was used to intubate for general anesthesia
- interventionNames
- Device: Tapered-shaped cuff tracheal tube
- type
- ACTIVE_COMPARATOR
- label
- Cylindrical-shaped cuff ETT group
- description
- A cylindrical-shaped cuff tube was used to intubate for general anesthesia
- interventionNames
- Device: Cylindrical-shaped cuff tracheal tube
Primary outcomes (2)
- measure
- The incidence of postoperative sore throat
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Female patients scheduled for elective breast cancer surgery performed in the supine position requiring tracheal intubation Exclusion Criteria: * Age \< 18 years or age \> 80 years * Diseases or anatomic abnormalities in the neck, larynx, or pharynx * Combined surgery such as breast reconstruction * Active pulmonary disease * Morbid obesity (body mass index ≥ 40 kg/m2) * Pregnancy * Refusal to join the study
References
Publications (7)
- RESULTMonroe MC, Gravenstein N, Saga-Rumley S. Postoperative sore throat: effect of oropharyngeal airway in orotracheally intubated patients. Anesth Analg. 1990 May;70(5):512-6. doi: 10.1213/00000539-199005000-00008. PMID 2331067
- RESULTChristensen AM, Willemoes-Larsen H, Lundby L, Jakobsen KB. Postoperative throat complaints after tracheal intubation. Br J Anaesth. 1994 Dec;73(6):786-7. doi: 10.1093/bja/73.6.786. PMID 7880666
- RESULTBiro P, Seifert B, Pasch T. Complaints of sore throat after tracheal intubation: a prospective evaluation. Eur J Anaesthesiol. 2005 Apr;22(4):307-11. doi: 10.1017/s0265021505000529. PMID 15892411
- RESULTLehmann M, Monte K, Barach P, Kindler CH. Postoperative patient complaints: a prospective interview study of 12,276 patients. J Clin Anesth. 2010 Feb;22(1):13-21. doi: 10.1016/j.jclinane.2009.02.015. PMID 20206846
- RESULTEl-Boghdadly K, Bailey CR, Wiles MD. Postoperative sore throat: a systematic review. Anaesthesia. 2016 Jun;71(6):706-17. doi: 10.1111/anae.13438. Epub 2016 Mar 28. PMID 27158989
- RESULTChang JE, Kim H, Han SH, Lee JM, Ji S, Hwang JY. Effect of Endotracheal Tube Cuff Shape on Postoperative Sore Throat After Endotracheal Intubation. Anesth Analg. 2017 Oct;125(4):1240-1245. doi: 10.1213/ANE.0000000000001933. PMID 28368938
- DERIVEDChen GC, Lo KL, Wu ZF, Chan SM, Cheng SY, Ko CL, Chu CM, Tseng WC. Comparison of the incidence and severity of postoperative sore throat and subglottic airway injury with cylindrical versus tapered cuff endotracheal tubes in women undergoing surgery for breast cancer: a randomized controlled trial. BMC Anesthesiol. 2025 Apr 12;25(1):181. doi: 10.1186/s12871-025-03040-y. PMID 40221641