Clinical trial · Interventional
Dyadic Life Review Intervention for Older Patients With Advanced Cancer) and Their Caregivers
A Pilot Randomized Controlled Trial (RCT) of a Dyadic Life Review Intervention for Older Patients With Advanced Cancer) and Their Caregivers
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): This study is closing early to accrual as of 04/10/2026 due to lower than anticipated enrollment, driven by recruitment challenges. The current findings will help develop strategies to improve these processes in future research.
Summary
Brief summary (as posted)
The purpose of this study is to test the feasibility of a pilot Randomized Controlled Trial (RCT) comparing Dyadic Life Review (DLR) intervention in older adults with advanced cancer and their caregivers to Care-as-Usual (CAU) group, which involves a referral to social work.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dyadic Life Review | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Dyadic Life Review
- description
- The Dyadic Life Review Arm (DLR) consists of 8 sessions delivered by a trained licensed clinician. Each session facilitates a recall of each phase of life. The patient and caregiver will each be asked structured questions to prompt reminiscence of memories from that phase of life. Interventionists are able to use clinical judgment to prompt further or ask follow-up questions or reflections. Additionally, the patient and caregiver will be asked to respond to the other dyad member's memory or reflection. Each session will have flexibility for clinical judgement.
- interventionNames
- Behavioral: Dyadic Life Review
- type
- NO_INTERVENTION
- label
- Case-As-Usual
- description
- The Care-As-Usual (CAU) arm will follow current practices for responding to patient distress. The CAU for patients involves a supportive follow-up phone call from the social work team to further assess the patient's experience of distress. In some instances, the social worker will use their clinical judgement to further refer the patient to community resources to support distress. The number of phone calls and any subsequent community referrals or appointments related to distress that occur will be tracked.
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
Show eligibility criteria text
Patient Inclusion Criteria: * Age ≥ 65 * Patient has a Stage III or IV advanced cancer diagnosis of any type * Score of 4 or more on National Comprehensive Cancer Network (NCCN) Distress Thermometer (DT)\* * Able to read and understand English Patient Exclusion Criteria: • Unable to identify caregiver to participate in study Caregiver Inclusion Criteria: * One caregiver must enroll with each patient for either subject to be eligible. * Caregivers will be selected by the patient when asked if there is a "significant other, spouse, romantic partner, or adult child with whom you discuss or can be helpful in health-related matters;" * Age 50 or older * Able to reach and understand English Caregiver Exclusion Criteria: • Caregivers unable to provide consent
References
Publications (0)
Data not yet available