Clinical trial · Observational
The Effects of Programmed Death-ligand 1 on Postoperative Pain for Lung Cancer Patients
NCT06503432CI-TRIAL-00080704unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The concentration of plasma programmed death-ligand 1(PD-L1) for lung cancer patients before video-assisted thoracoscopic surgery is detected. According to the distribution of plasma concentration, patients are divided into high or low expression of PD-L1. Differences in acute and chronic postoperative pain are compared between two groups of patients. And effects of PD-L1 expresion on postoperative pain in lung cancer patients are explained.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Postoperative Pain | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- high expression of programmed death-ligand 1
- description
- According to the distribution of PD-L1 concentration levels in the plasma, participants were divided into two groups: high expression of PD-L1 (PD-L1(H)) and low expression of PD-L1 (PD-L1(L)).
- label
- low expression of programmed death-ligand 1
- description
- According to the distribution of PD-L1 concentration levels in the plasma, participants were divided into two groups: high expression of PD-L1 (PD-L1(H)) and low expression of PD-L1 (PD-L1(L)).
Primary outcomes (1)
- measure
- the incidence of chronic pain after surgery
- timeFrame
- 3 months after surgery
- description
- Patients were followed up by the Brief Pain Inventory questionnaire about the details of chronic pain.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. American Society of Anesthesiologists physical status I-IV (males and females). 2. 18-80 years of age. 3. Patients undergoing video-assisted thoracoscopic surgery for malignant lung disease. Exclusion Criteria: 1. History of opioid abuse. 2. Known psychiatric disorders. 3. Unexpected conversion to thoracotomy or transferred to intensive care unit for further treatment. 4. Combined with other surgeries or sites.
References
Publications (0)
Data not yet available
No reference posted for this study.