Clinical trial · Interventional
CALM Psychotherapy in Patients With Metastatic Cancer in Chile
Preliminary Efficacy and Acceptability of CALM Psychotherapy in Chile
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with metastatic cancer experience multidimensional challenges that increase the risk of emotional distress, which must be addressed by the health team. Chile lacks evidence on effective therapeutic interventions in this population. CALM is a brief, individual (with the presence of a caregiver in one or more sessions) and evidence-based psychotherapy developed at The Princess Margaret Cancer Center. It consists of an intervention of 3 to 6 psychotherapy sessions over a period of 3 to 6 months. The Global CALM program aims to expand CALM research around the world, a program to which FALP has subscribed. Objective: To evaluate the preliminary efficacy of CALM in a sample of patients with metastatic cancer in Chile. Phase 2 study of preliminary, pseudo-experimental efficacy, without a control group. The study will be carried out in Falp and Corporación Valientes.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| CALM psychotherapy | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- CALM arm
- description
- patients receiving CALM sessions
- interventionNames
- Behavioral: CALM psychotherapy
Primary outcomes (4)
- measure
- depressive symptoms
- timeFrame
- 3 months
- description
- Patient Health Questionnaire 9- Higher score means higher depression
- measure
- depressive symptoms
- timeFrame
- 6 months
- description
- Patient Health Questionnaire 9- Higher score means higher depression
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * be ≥18 years of age; * be fluent in Spanish; * be able to give informed consent; and * have received a diagnosis of advanced or metastatic solid tumor cancer with a reduced life expectancy but greater than six months. Exclusion Criteria: * significant verbal communication difficulties; * cognitive impairment indicated by the clinical team or in the patient's file. * Patients currently in psychotherapy. * Active suicidal ideation
References
Publications (0)
Data not yet available