Clinical trial · Interventional
Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
The Efficacy of Dexamethasone Versus Magnesium Sulphate Added to Bupivacaine Used in Erector Spinae Plane Block for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aim of the study: The current study aims to compare the effect of adding dexamethasone versus magnesium sulfate to bupivacaine in ultrasound-guided erector spinae plane block on the severity of postoperative pain. Primary Objectives: \- To compare the effect of ESPB without additives to the effect of adding dexamethasone and to the impact of adding magnesium sulfate in the form of post-operative morphine consumption
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Renal Neoplasm | Kidney Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25% | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Normal saline
- description
- receiving erector spinae block with 27ml bupivacaine 0.25% + 3 ml NS
- interventionNames
- Procedure: ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%
- type
- ACTIVE_COMPARATOR
- label
- magnesium sulphate 10%
- description
- receiving erector spinae block with 27 ml bupivacaine 0.25% + 3 ml magnesium sulphate 10%
- interventionNames
- Procedure: ultrasound guided Erector Spinae Plane Block using 27ml bupivacaine 0.25%
- type
- ACTIVE_COMPARATOR
- label
- dexamethasone
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Adult (18 - 65) * Patients undergoing unilateral nephrectomy * ASA II / III Exclusion Criteria: * Patient refusal * Age less than 18 years * Allergy to any of the studied medications * Mid line incision * Bilateral nephrectomy * Distorted anatomy of the back (e.g. kyphoscoliosis) * Known neurologic disorders, psychiatric disorder or chronic pain * Local infection * Hemodynamic instability
References
Publications (0)
Data not yet available