Clinical trial · Observational
Research on Nutritional Risk Indexes and Inflammatory Indicators in Postoperative Complications and Prognosis of Epithelial Ovarian Cancer Patients
Influence of Nutritional Risk Indexes and Inflammatory Indicators on Postoperative Complications and Prognosis of Epithelial Ovarian Cancer and Construction of Prediction Models
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this observational study is to explore the influence and predictive significance of nutritional risk indicators and inflammatory indicators on postoperative complications and prognosis of patients with epithelial ovarian cancer (EOC). The main question it aims to answer is: Can preoperative nutritional risk and inflammatory indexes predict postoperative complications? Do preoperative nutritional risk and inflammatory indexes better predict the prognosis of patients with epithelial ovarian cancer? Which index is the best predictor of postoperative complications or prognosis for patients?
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Epithelial Ovarian Cancer | Ovarian Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (2)
- label
- Low [index] group
- description
- The patients were grouped according to the cut-off value of each index, and the patients whose index value was lower than the cut-off value were classified as the Low \[index\] group.
- label
- High [index] group
- description
- The patients were grouped according to the cut-off value of each index, and the patients whose index value was higher than the cut-off value were classified as the High \[index\] group.
Primary outcomes (3)
- measure
- Postoperative Complications
- timeFrame
- Within 30 days after surgery
- description
- Surgical complications within 30 days after comprehensive staging or cytoreductive surgery recorded according to the Clavien-Dindo grading system
- measure
- Progression-free survival
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- Female
Show eligibility criteria text
Inclusion Criteria: 1. histologically confirmed primary epithelial ovarian, peritoneal, and fallopian tube cancers. 2. patients received comprehensive staged surgery or debulking surgery. 3. available data of laboratory examination within 7 days before the surgery. Exclusion Criteria: 1. borderline ovarian tumor. 2. receipt of neoadjuvant chemotherapy. 3. presence of other conditions influencing laboratory data, like hepatitis, kidney disease, autoimmune diseases, infectious diseases, blood disease, etc. 4. concurrent cancer in other organs. 5. absence of surgery or biopsy only. 6. multiple staged surgeries.
References
Publications (1)
- DERIVEDLiu X, Li M, Zhao Y, Jiao X, Yu Y, Li R, Zeng S, Chi J, Ma G, Huo Y, Peng Z, Liu J, Zhou Q, Zou D, Wang L, Li Q, Wang J, Yao S, Chen Y, Ma D, Hu T, Gao Q. The impact of preoperative immunonutritional status on postoperative complications in ovarian cancer. J Ovarian Res. 2025 Apr 29;18(1):88. doi: 10.1186/s13048-025-01624-3. PMID 40301987