Clinical trial · Observational
Vaginal Ecosystem and Network in the United States Study
Comprehensive Registry and PCR Analysis of the Vaginal Microbiome in Women: Data Collection in Healthy and Diseased States
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions. Specifically, the research aims to investigate how imbalances in microbial communities, such as the overgrowth of pathogenic bacteria or the depletion of beneficial ones, are linked to conditions like Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Vaginal Atrophy, and others. By employing PCR testing and the outcomes of next-generation sequencing (NGS) of the microbiome, the study seeks to identify distinct microbial profiles and patterns that are characteristic of each condition. This nuanced understanding is expected to lead to more accurate and early diagnosis, facilitating personalized and effective treatment strategies that go beyond the conventional, often indiscriminate use of antibiotics.
Conditions
Conditions (11)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bacterial Vaginosis | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Candidiasis | — | UNRESOLVED | — |
| Desquamative Inflammatory Vaginitis | — | UNRESOLVED | — |
| Endometriosis | — | UNRESOLVED | — |
| Genitourinary Syndrome of Menopause | — | UNRESOLVED | — |
| Lichen Planus | — | UNRESOLVED | — |
| Lichen Sclerosus | — | UNRESOLVED | — |
| Ureaplasma Infections | — | UNRESOLVED |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Vaginal Swab Collection | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (13)
- label
- Premenopausal Healthy
- description
- Premenopausal Healthy
- interventionNames
- Diagnostic Test: Vaginal Swab Collection
- label
- Perimenopausal Healthy
- description
- Perimenopausal Healthy
- interventionNames
- Diagnostic Test: Vaginal Swab Collection
- label
- Postmenopausal Healthy
- description
- Postmenopausal Healthy
- interventionNames
- Diagnostic Test: Vaginal Swab Collection
- label
- Bacterial Vaginosis
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 89 Years
Show eligibility criteria text
Inclusion Criteria: * Healthy cis-gender women between ages 18 and 89 Exclusion Criteria: * Pregnant or trying to conceive (i.e. IVF, IUI)
References
Publications (0)
Data not yet available