Clinical trial · Interventional
Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage
Using Polyglycolic Acid Mesh Prevents Cerebrospinal Fluid Leakage: Clinical Application to Endoscopic Endonasal Transsphenoidal Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The papers propose a new method to prevent postoperative cerebrospinal fluid leakage. Doctors use the absorbable polyglycolic acid (PGA) and fibrin glue to repair in surgery, prevent cerebrospinal fluid leakage and reduce the necessity of postoperative lumbar drainage after surgery. This study will analyze the changes in cerebrospinal fluid leakage in patients with pituitary tumors and skull base tumors after surgery, and further understand the effectiveness of Neoveil , as the basis for the development of new treatments.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cerebrospinal Fluid Leakage | — | UNRESOLVED | — |
| Pituitary Tumor | Pituitary Gland Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| polyglycolic acid(Neoveil) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Using polyglycolic acid mesh
- interventionNames
- Device: polyglycolic acid(Neoveil)
Primary outcomes (1)
- measure
- Mesurement CSF leakage grade change after surgery
- timeFrame
- 6 months
- description
- Confirmation of change in CSF leakage grafe after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 20 Years
Show eligibility criteria text
A. Inclusion criteria 1\. Patients with primary or recurrent pituitary tumors require endoscopic nasal surgery. B. Exclusion criteria 1. Patients with pituitary gland tumors who do not receive surgical treatment. 2. Patients with other brain tumors. 3. Patients allergic to polyglycolic acid (PGA). 4. Patients who have had previous radiation therapy or chemotherapy.
References
Publications (0)
Data not yet available