Clinical trial · Interventional
Heart Analysis in GATED-PET in Patients Having a Gallium-68-DOTATOC PET/CT Exam for Oncology Indication
GATED-PET Heart Analysis in Patients Having a Gallium-68--DOTATOC PET/CT Exam for Oncology Indication
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Gallium-68-DOTATOC binds primarily with high affinity to somatostatin subtype 2 (SSTR2) receptors and these somatostatin receptors are also overexpressed on inflammation cells when activated. The hypothesis is that the GATED mode on a Gallium-68-DOTATOC cardiac recording would be able to highlight abnormalities that could be correlated with the age of the patients and their cardiovascular risk factors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cardiac Inflammation | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cardiac ECG-gated PET imaging will added | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Patients
- description
- Person for whom a 68Ga-DOTATOC PET/CT exam is requested as part of the diagnostic or pre-therapeutic assessment of a neuroendocrine tumor
- interventionNames
- Other: Cardiac ECG-gated PET imaging will added
Primary outcomes (1)
- measure
- Relationship between the captation of radiotracer and the cardiovascular disease
- timeFrame
- 1 day
- description
- Measurement of myocardial activity
Secondary outcomes (1)
- measure
- Relationship between the captation of radiotracer and the troponin value
- timeFrame
- 1 day
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Persons who have received complete information on the organization of the research and who have signed the informed consent and: * Age ≥ 18 years old. * Having read and understood the information document. * Affiliated to a social security scheme. Person for whom a 68Ga-DOTATOC PET/CT exam is requested as part of the diagnostic or pre-therapeutic assessment of a neuroendocrine tumour. Exclusion Criteria: Person with * Hypersensitivity during previous use of 68Ga-DOTATOC * Impossibility of performing a PET-CT (patient agitated, confused, etc.). * History of heart disease, * Severe arrhythmia that does not allow the PET synchronized with the ECG * Severe renal insufficiency (GFR \<30 ml/min/1.73 m2) * Treated with a somatostatin analogue. * Cushing's syndrome * Pregnant woman, likely to be or breastfeeding * Adult subject to a legal protection measure (guardianship, curators, legal safeguard) * Person of legal age unable to express their consent * Person deprived of liberty by a judicial or administrative decision * Person, subject to psychiatric care under articles L. 3212-1 and L. 3213-1
References
Publications (0)
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