Clinical trial · Observational
Prediction Model for Advanced Gastric Cancer in Elderly
Prediction of Long-term Survival and Chemotherapy Benefit in Elderly Advanced Gastric Cancer Patients Based on the mCNS Model of Nutritional Control State Score and Sarcopenia.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to develop and validate a Nomogram (mCNS) model for predicting long-term survival in elderly patients following curative resection for advanced gastric cancer. The study is a retrospective multi-center analysis involving 924 gastric cancer patients treated at the Department of Gastrointestinal Surgery of the Affiliated Union Hospital of Fujian Medical University between 2009 and 2013, and 512 patients aged 65 and above who underwent gastric resection at the Affiliated Zhongshan Hospital of Dalian University between 2011 and 2018. An online prognostic tool is introduced to assist clinicians in predicting patient prognosis and customizing treatment and follow-up strategies.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Aged | — | UNRESOLVED | — |
| Stomach Neoplasms | Gastric Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- 5-Year Overall Survival
- timeFrame
- 5 years or 60 months.
- description
- The proportion of patients who are alive at five years after treatment for elderly gastric cancer patients.
Secondary outcomes (2)
- measure
- 3-Year Overall Survival
- timeFrame
- 3 years or 36 months.
- description
- The proportion of patients who have survived without any signs or symptoms of gastric cancer for 3 years after the initial treatment.
- measure
- 1-Year Overall Survival
- timeFrame
- 1 years or 12 months.
- description
- The proportion of patients who have survived without any signs or symptoms of gastric cancer for 1 years after the initial treatment.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * Confirmed as primary gastric adenocarcinoma by preoperative gastric endoscopy pathology; * Underwent R0 laparoscopic radical gastrectomy for gastric cancer; * Pathological stage T2-4a-N+; * Age ≥ 65 years. Exclusion Criteria: * Pathological stage T1 and T2N0; * Age \< 65 years; * Presence of peritoneal or distant metastasis confirmed before or during surgery; * Received neoadjuvant chemotherapy before surgery; * Remnant gastric cancer; * Emergency surgery or palliative exploratory surgery; * Preoperative abdominal CT scan not available or preoperative examination time \> 1 month; * Survival time less than 1 month; * Incomplete clinical and pathological data.
References
Publications (0)
Data not yet available