Clinical trial · Observational
CMR Right Ventricular Contractile Reserve Following Lung Resection
Assessment of Right Ventricular Contractile Reserve Following Lung Resection by Dobutamine Stress Cardiac Magnetic Resonance: a Feasibility Study
NCT06465277CI-TRIAL-00081310unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Feasibility study investigating CMR dobutamine stress testing before and after lung resection
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia | — | UNRESOLVED | — |
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Surgery | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cardiac biomarker sample | Diagnostic Test | — | UNRESOLVED |
| Dobutamine stress CMR | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Lung resection
- description
- 12 patients undergoing lobectomy. Pre and post-operative dobutamine stress CMR testing and cardiac biomarker testing.
- interventionNames
- Diagnostic Test: Dobutamine stress CMR
- Diagnostic Test: Cardiac biomarker sample
- label
- Oesophagectomy
- description
- 15 patients Peri-operative cardiac biomarker testing.
- interventionNames
- Diagnostic Test: Cardiac biomarker sample
- label
- Gastrectomy
- description
- 15 patients Peri-operative cardiac biomarker testing.
- interventionNames
- Diagnostic Test: Cardiac biomarker sample
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria:
* 1\) Provision of informed consent 2) Age \>16 years 3) Planned elective
1. lobectomy lung resection or
2. oesophagectomy surgery with one lung ventilation or
3. gastrectomy
Exclusion Criteria:
1. Pregnancy
2. On-going participation in any investigational research which could undermine the scientific basis of the study
3. Atrial fibrillation at baseline
4. Any contraindication to
a. CMR, i. Cardiac pacemaker, artificial heart valve, neurostimulator, cochlear implant ii. Aneurysm clips iii. Metal injuries to the eye iv. Loose metal in a part of the body b. Dobutamine stress testing as per the Society for Cardiovascular Magnetic Resonance64 i. Severe systemic arterial hypertension (≥220/120 mmHg) ii. Unstable angina pectoris iii. Severe aortic valve stenosis (peak aortic valve gradient \>60mmHg or aortic valve area \< 1cm2) iv. Complex cardiac arrhythmias including uncontrolled atrial fibrillation v. Hypertrophic obstructive cardiomyopathy vi. Myocarditis, endocarditis, or pericarditis vii. Uncontrolled heart failure
5. Lung resection specific
1. Wedge, segmental or sub-lobar lung resection
2. Pneumonectomy
3. Isolated right middle lobectomy
\-References
Publications (0)
Data not yet available
No reference posted for this study.