Clinical trial · Interventional
Robotic Natural Orifice Specimen Extraction Surgery Compared to Robotic Assisted Surgery for Median Rectal Cancer
the First Affiliated Hospital of Nanchang University
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the short-term outcomes of roboric natural orifice specimen extraction surgery (NOSES-II) compared to conventional assisted robotic surgery in the treatment of median rectal cancer. The main question it aims to answer is: is it safe and feasible to perform roboric natural orifice specimen extraction surgery (NOSES-II) for median rectal cancer? What are the advantages of roboric natural orifice specimen extraction surgery (NOSES-II) compared to conventional assisted robotic surgery for median rectal cancer.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Middle Rectal Cancer | — | UNRESOLVED | — |
| Natural Orifice Specimen Extraction Surgery | — | UNRESOLVED | — |
| Robotic | — | UNRESOLVED | — |
| Short-term Outcomes | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| robotic natural orifice specimen extraction surgery | Procedure | — | UNRESOLVED |
| robotic transabdominal specimen extraction surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- robotic natural orifice specimen extraction surgery for middle rectal cancer
- description
- After the body is free, the tumor segment of the bowel is pulled out through the anus. Excise the tumor segment of the colon outside the anus.
- interventionNames
- Procedure: robotic natural orifice specimen extraction surgery
- type
- SHAM_COMPARATOR
- label
- robotic transabdominal specimen extraction surgery for middle rectal cancer
- description
- After internal mobilization, the tumor segment of the bowel was removed through an abdominal incision. Excise the tumor segment of the bowel outside the incision.
- interventionNames
- Procedure: robotic transabdominal specimen extraction surgery
Primary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. The age is more than 18 years old and less than or equal to 85 years old 2. Eastern Cooperative Oncology Group score ≤2 3. Preoperative pathological diagnosis of rectal adenocarcinoma 4. cT1-3NxM0 median rectal cancer defined by preoperative contrast-enhanced MRI 5. The maximum diameter of tumor ≤5cm on preoperative enhanced MRI 6. The body can tolerate the operation and sign the informed consent Exclusion Criteria: 1. multiple primary colorectal cancer 2. recurrent rectal cancer 3. preoperative neoadjuvant chemoradiotherapy 4. complicated with intestinal obstruction or intestinal bleeding requiring emergency surgery 5. previous anal surgery history 6. BMI≥30kg/m2 7. severe mental illness
References
Publications (1)
- DERIVEDLi TY, Min FZ, Yu T, Luo AL, Ye SP. A randomized controlled trial comparing robotic NOSES versus robotic TME for Mid-rectal cancer: short-term oncological and perioperative outcomes. J Robot Surg. 2026 May 21;20(1):516. doi: 10.1007/s11701-026-03494-3. PMID 42162355