Telehealth-based Symptom Management for Veterans Treated With Selinexor

Inclusion Criteria:

* Diagnosis of B-cell malignancy: either relapsed or refractory multiple myeloma or diffuse large B-cell lymphoma, meeting the FDA-approved indication for Selinexor treatment.
* Requiring therapy as assessed by the treating oncology provider.
* Prior authorization drug request for selinexor approved by VA oncology pharmacist.
* Subject age 18 years or older.
* Subject willing and able to perform video or telephone research visits.
* Subjects must be able to read and comprehend English.
* Subject must be a Veteran receiving cancer care from a VA facility affiliated with the National Teleoncology Program.
* Patients must be enrolled prior to starting Selinexor.

Exclusion Criteria:

* Any prior or current therapy with selinexor.
* Any medical, psychiatric, or cognitive issue that the principal investigator or the subject's oncologists believes would prevent participation or completion of the study.
* Individuals who are vulnerable to coercion or undue influence.
* Any individuals or populations that may temporarily or permanently require additional considerations include such as those susceptible to coercion or undue influence (e.g., patients with limited or no treatment options, socially and economically disadvantaged persons).
* Current selinexor therapy that is part of an investigational clinical trial.