Clinical trial · Interventional
Self-Administered Relaxing Acupressure to Reduce Fatigue in Adolescent and Young Adult Cancer Survivors
A Pilot Study of Self-Administered Acupressure for Fatigue Among Adolescent and Young Adult (AYA) Cancer Survivors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial tests the feasibility of self-administered relaxing acupressure on fatigue in adolescent and young adult (AYA) cancer survivors. Acupressure, a type of complementary or alternative medicine, is the application of pressure or localized massage to specific sites on the body to control symptoms. Relaxing acupressure has been shown to improve cancer-related fatigue (CRF) in adults, however, less is known about the impact of relaxing acupressure on CRF in AYA cancer survivors."
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hematopoietic and Lymphatic System Neoplasm | Hematopoietic and Lymphatic System Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Malignant Solid Neoplasm | Malignant Solid Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Acupressure Therapy | Procedure | — | UNRESOLVED |
| Internet-Based Intervention | Other | — | UNRESOLVED |
| Interview | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- ARM I (relaxing acupressure)
- description
- Patients receive access to acupressure mobile application and self-administer relaxing acupressure to 9 acupoints over 27 minutes QD for 6 weeks.
- interventionNames
- Procedure: Acupressure Therapy
- Other: Internet-Based Intervention
- Other: Interview
- Other: Questionnaire Administration
- type
- PLACEBO_COMPARATOR
- label
- ARM II (sham acupressure)
- description
- Patients receive access to acupressure mobile application and self-administer sham acupressure to non-acupressure point locations over 27 minutes QD for 6 weeks.
- interventionNames
- Procedure: Acupressure Therapy
- Other: Internet-Based Intervention
- Other: Interview
- Other: Questionnaire Administration
Primary outcomes (2)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria: * 15 - 39 years old * At least three months post cancer treatment (e.g., surgery, radiation or chemotherapy). Participants receiving maintenance hormonal or targeted therapies will be allowed to enroll as determined by the study investigator * Report clinically relevant fatigue in the past seven days (Patient Reported Outcomes Measurement Information Systems \[PROMIS\] Fatigue 4a scores ≥ 55) * Speak / read English * CRF started at or after the diagnosis of cancer * Completed cancer treatment within the past five years Exclusion Criteria: * Diagnosis of untreated anemia, mood disorder, or hypothyroidism * Plan to begin new pharmacological, psychological, or other treatments (i.e., physical therapy or dietary supplements) for CRF during the study. Although, participants may continue usual treatments for CRF if the treatments were initiated at least eight weeks prior to study enrollment, and the dose has not changed * Plan to become pregnant or lactating during the study period * Received acupressure or acupuncture in the past year
References
Publications (1)
- DERIVEDKnoerl R, Jardine J, Chugh R, Fecher LA, Henry NL, Joquico M, Karimi Y, Ploutz-Snyder R, Taylor S, Walling E, Zick S. Determining the feasibility of self-administered relaxing acupressure for fatigue among adolescent and young adult cancer survivors. Support Care Cancer. 2026 Jun 24;34(7):684. doi: 10.1007/s00520-026-10917-2. PMID 42337155