Clinical trial · Interventional
Liposomal Bupivacaine vs Ropivacaine for TAPBs
Liposomal Bupivacaine vs Ropivacaine for Ultrasound-guided Transversus Abdominis Plane Blocks in Laparoscopic Lower Abdominal Tumor Resection: A Prospective Randomized Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Few studies have compared the efficacy of ultrasound (US)-guided TAP blocks with Liposomal bupivacaine(LB) versus ropivacaine in reducing postoperative opioid usage in patients undergoing laparoscopic lower abdominal tumor Resection. Therefore, we are conducting this prospective, randomized controlled trial to compare the postoperative analgesic effects of LB and ropivacaine for TAP blocks among patients undergoing laparoscopic colorectal procedures.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Abdominal Tumor | — | UNRESOLVED | — |
| Liposomal Bupivacaine | — | UNRESOLVED | — |
| Postoperative Analgesia | — | UNRESOLVED | — |
| Ropivacaine | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Liposomal Bupivacaine | Drug | — | UNRESOLVED |
| Ropivacaine | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Liposomal Bupivacaine group
- description
- Liposomal Bupivacaine was used in the group
- interventionNames
- Drug: Liposomal Bupivacaine
- type
- ACTIVE_COMPARATOR
- label
- Ropivacaine group
- description
- Ropivacaine was used in this group
- interventionNames
- Drug: Ropivacaine
Primary outcomes (1)
- measure
- Postoperative opioid use
- timeFrame
- 3 days postoperatively
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patients undergoing laparoscopic resection of lower abdominal tumors 2. ASA grade II-III 3. Age: 18-70 years. Exclusion Criteria: 1. (1) The patient does not agree to participate in the clinical study 2. (2) The patient has a clear history of opioid tolerance or allergy 3. (3) The patient has a history of local anesthetic allergy 4. (4) Previous history of dementia, mental illness or other central nervous system diseases 5. (5) Have a history of chronic pain or are taking opioids and other analgesics 6. (6) Patients are generally in poor condition with a history of serious diseases of cardiovascular system, respiratory system, digestive system, urinary system or central nervous system, and may not survive for more than 3 months 7. (7) The patient had any of the following conditions in the 12 months before surgery: myocardial infarction, severe/unstable angina pectoris, coronary artery bypass grafting, congestive heart failure, cerebrovascular accident, pulmonary embolism 8. (8) Pregnant women 9. (9) Unable to cooperate with follow-up or poor compliance 10. (10) Patients with acute myocardial infarction, cardiac arrest or shock during surgery or hospitalization 11. (11) ASA score above grade III.
References
Publications (0)
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