Clinical trial · Interventional
Evaluating Procedures for a Study of the AYA Survivors Coping and Emotional Needs Toolkit
Evaluating the Feasibility and Acceptability of Study Procedures for a Full Factorial Trial of the AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators developed a digital intervention that aims to help adolescent and young adult cancer survivors (AYAs) manage symptoms of depression. This tool includes daily mood tracking, a psychoeducational module about cancer and depression, four components that are based on evidence-based interventions for depression. The goal of this study is to evaluate the acceptability of procedures for a future trial in which the investigators will test which component or combination of components meaningfully contribute to improvements in depressive symptoms among AYAs. Additionally, the investigators will evaluate study feasibility as well as intervention acceptability, satisfaction, usability, and engagement.
Conditions
Conditions (5)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adolescent | — | UNRESOLVED | — |
| Adult | — | UNRESOLVED | — |
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Depression | — | UNRESOLVED | — |
| Young Adult | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| AYA Survivors Coping and Emotional Needs Toolkit (ASCENT) | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (16)
- type
- EXPERIMENTAL
- label
- Condition 1
- description
- Feeling component of ASCENT (psychoeducation about AYA cancer survivorship and depression).
- interventionNames
- Behavioral: AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- type
- EXPERIMENTAL
- label
- Condition 2
- description
- Feeling component of ASCENT (psychoeducation about AYA cancer survivorship and depression); Positivity component of ASCENT (an adaptation of a suite of evidence-based positive psychology interventions that aims to help AYAs savor the good things in life, use their strengths, and practice gratitude and kindness).
- interventionNames
- Behavioral: AYA Survivors Coping and Emotional Needs Toolkit (ASCENT)
- type
- EXPERIMENTAL
- label
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria: * Age at enrollment (adolescents 15-17, emerging adults 18-25, young adults 26-39) * Age at diagnosis (adolescents 12-17, emerging adults 15-25, young adults 15-39) * Time since completion of treatment: 1 month to 5 years * Language: Fluent in English (spoken and written) * Technology: Own smart phone with data plan Exclusion Criteria: * Mental Health: Current diagnosis of severe or persistent mental illness * Suicidality: Severe suicidal ideation (including plan and intent)
References
Publications (1)
- DERIVEDIngram KM, Glock R, Williamson L, Coffey A, Anctil R, Augustinovic A, Yang D, Victorson D, Schoemann AM, Liles D, Salsman JM. Evaluating the feasibility and acceptability of study procedures for a full factorial trial of ASCENT: protocol for a randomized pilot. Pilot Feasibility Stud. 2025 Nov 24;11(1):147. doi: 10.1186/s40814-025-01728-z. PMID 41287126