Clinical trial · Observational
The Effect of Ultrasonography-guided Fascial Plane Blocks in Breast Cancer Surgery Patients
The Effect of Ultrasonography-guided Pectoserratus Plane Block, Erector Spina Plane Block and Serratus Anterior Plane Block on Postoperative Opioid Consumption, Recovery Quality and Chronic Pain in Breast Cancer Surgery Patients
NCT06419504CI-TRIAL-00089846completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of this study was to evaluate the efficacy of serratus anterior plane (SAP) block, pectoserratus plane (PECS II) block, and erector spinae plane (ESP) block on postoperative acute pain, quality of recovery and chronic pain in breast cancer surgery patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Control group | Other | — | UNRESOLVED |
| ESP block group | Other | — | UNRESOLVED |
| PECS II block group | Other | — | UNRESOLVED |
| SAP block group | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (4)
- label
- SAP block group
- description
- Before the surgery, US-guided SAP block will be performed
- interventionNames
- Other: SAP block group
- label
- PECS II block group
- description
- Before the surgery, US-guided PECS II block will be performed
- interventionNames
- Other: PECS II block group
- label
- ESP block group
- description
- Before the surgery, US-guided ESP blockwill be performed
- interventionNames
- Other: ESP block group
- label
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
- Maximum age
- 65 Years
Show eligibility criteria text
Inclusion Criteria: * elective breast surgery (modified radical mastectomy, breast conserving surgery, simple mastectomy, axillary lymph node dissection, etc.), * 18 to 65 years old, * American Society of Anaesthesiology (ASA) score I-III * body mass index (BMI) \<32 kg/m2 Exclusion Criteria: * contraindications to the block applications * history of mental or neurological disorders * history of chronic opioid use * chronic alcoholism * substance use * treatment of chronic pain * severe liver and kidney disease * uncooperative patients * patients scheduled for bilateral mastectomy
References
Publications (2)
- BACKGROUNDWang S, Shi J, Dai Y, Zhang J, Liu Q, Yang P, Zhu N. The effect of different nerve block strategies on the quality of post-operative recovery in breast cancer patients: A randomized controlled study. Eur J Pain. 2024 Jan;28(1):166-173. doi: 10.1002/ejp.2178. Epub 2023 Sep 1. PMID 37655864
- BACKGROUNDFujii T, Shibata Y, Akane A, Aoki W, Sekiguchi A, Takahashi K, Matsui S, Nishiwaki K. A randomised controlled trial of pectoral nerve-2 (PECS 2) block vs. serratus plane block for chronic pain after mastectomy. Anaesthesia. 2019 Dec;74(12):1558-1562. doi: 10.1111/anae.14856. Epub 2019 Sep 19. PMID 31535722