Clinical trial · Observational
Vienna Hypothermic Oxygenated Machine Perfusion Study
Vienna Hypothermic Oxygenated Machine Perfusion for Liver Transplantation Study
NCT06418165CI-TRIAL-00077243VIHOMPSrecruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this observational cohort study data on all patients undergoing liver transplantation after hypothermic oxygenated machine perfusion at Medical University of Vienna will be prospectively recorded. Investigation of short- and long-term outcome in this cohort will be conducted.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| End Stage Liver Disease | — | UNRESOLVED | — |
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Incidence of ischemic-type biliary lesions
- timeFrame
- Within one year after liver transplantation
- description
- Non-anastomotic stenosis, post-transplant cholangiopathy
Secondary outcomes (3)
- measure
- Rate of early allograft dysfunction
- timeFrame
- Evaluated within the first 7 postoperative days
- description
- Deviation of bilirubin, transaminases or international normalised ratio
- measure
- Rate of primary non-function
- timeFrame
- Evaluated in the immediate postoperative period, specifically within the first postoperative week
- measure
- Incidence of re-transplantation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * patients undergoing liver transplantation with the use of hypothermic oxygenated machine perfusion * age ≥ 18 years Exclusion Criteria: * pregnancy * partial grafts * the anatomical integrity of the liver is not preserved in a way that makes the perfusion of the liver possible
References
Publications (1)
- DERIVEDPereyra D, Dingfelder J, Riha M, Kacar S, Rauter L, Becker N, Saffarian Zadeh T, Tortopis C, Starlinger P, Ristl R, Silberhumer G, Salat A, Soliman T, Berlakovich G, Gyoeri G. Dual hypothermic oxygenated machine perfusion of the liver reduces post-transplant biliary complications: a retrospective cohort study. Int J Surg. 2024 Dec 1;110(12):7909-7918. doi: 10.1097/JS9.0000000000002115. PMID 39422535