Clinical trial · Observational
Genetics in the Progression of Nephropathies
The Genetic Contribution to Progression of Kidney Disease
NCT06416761CI-TRIAL-00077215recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study evaluates the role of genetic in the development and progression of different nephropaties with particular attention to: * AKI * CKD * Hypertension * ADPKD * CKD-MBD * Patients with decompensated heart failure undergoing either medical or surgery therapy * Patients with hematologic cancer exposed to chemotherapeutic agents or undergoing allogeneic bone marrow transplantation * glomerular diseases
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| ADPKD | — | UNRESOLVED | — |
| AKI | — | UNRESOLVED | — |
| Bone Marrow Transplant Complications | — | UNRESOLVED | — |
| CKD | — | UNRESOLVED | — |
| CKD (Chronic Kidney Disease) Stage 5D | — | UNRESOLVED | — |
| Ckd-Mbd | — | UNRESOLVED | — |
| Hematologic Malignancy | Hematopoietic and Lymphoid Cell Neoplasm | ALIAS | 0.90 |
| Hypertension | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| genetic polymorphisms | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with acute or chronic nephropathy
- description
- 1. Patients with chronic nephropathies 2. Patients with acute nephropathy 3. Patients with nephrectomy 4. Candidate Patients to major surgery 5. Patients with decompensated heart failure undergoing either medical or surgical therapy 6. Acute critically ill patients (e.g sepsis, post-operative) 7. Patients with hypertension 8. Patients with hematologic cancer exposed to chemotherapeutic agents or undergoing allogeneic bone marrow transplantation. 9. Long-term surviving patients who received bone marrow transplantation.
- interventionNames
- Genetic: genetic polymorphisms
Primary outcomes (1)
- measure
- difference in glomerular filtration rate according to genetic profile
- timeFrame
- from days to 35 years
- description
- eGFR value
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: . presence of specific renal disease Exclusion Criteria: * to be evaluated in the different sub-protocols
References
Publications (0)
Data not yet available
No reference posted for this study.