Clinical trial · Observational
Prediction of Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma Based on Ultrasound and Cytological Images
An Interpretable Multimodal Model Based on Cytology Ultrasound Noninvasively Predicts Lymph Node Metastasis in cN0 Papillary Thyroid Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Rising thyroid carcinoma rates, with papillary thyroid carcinoma (PTC) as the main type (85-90% of cases), often show early cervical lymph node spread. This increases the risk of PTC patients for recurrence and death. A new study's multimodal model fuses preoperative US and cytology images to better predict lymph node metastasis, aiming to improve treatment plans, reduce unnecessary surgeries, and enhance patient outcomes.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymph Node Metastasis | — | UNRESOLVED | — |
| Papillary Thyroid Carcinoma | Thyroid Gland Papillary Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Thyroidectomy and lymph node dissection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Cohort with Lymph Node Metastasis
- description
- Depending on the pathological findings, it is classified as the presence of lymph node metastases.
- interventionNames
- Procedure: Thyroidectomy and lymph node dissection
- label
- Cohort without Lymph Node Metastasis
- description
- Depending on the pathological findings, it is classified as the absence of lymph node metastases.
- interventionNames
- Procedure: Thyroidectomy and lymph node dissection
Primary outcomes (1)
- measure
- Presence or absence of lymph node metastasis
- timeFrame
- October 2024
- description
- All surgical specimens were subjected to paraffin-embedded histopathological examination，depending on the pathological findings, it is classified as the presence or absence of lymph node metastases.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Underwent thyroidectomy and bilateral lymph node dissection with pathological confirmation of PTC * Completed US examination within one week before surgery * Underwent preoperative us-guided FNAC * Completed cytological images at 400× magnification under a microscope Exclusion Criteria: * Patients who underwent only unilateral thyroidectomy * Patients with cervical lymph nodes shown on preoperative ultrasound
References
Publications (0)
Data not yet available