Clinical trial · Observational
Impact of Hepatectomy on HCC Recurrence
Impact of Major Hepatectomy on Recurrence After Resection of Hepatocellular Carcinoma at China Liver Cancer Staging (CNLC) Stage : a Propensity Score Matching Study
NCT06390228CI-TRIAL-00076594HCCcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Hepatectomy is the first option for the treatment of hepatocellular carcinoma(HCC) at CNLC Ib stage. HCC patients who undergo curative hepatectomy may experience varying remnant liver volumes and thus leads to different oncological outcomes.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma Stage I | Hepatocellular Carcinoma | CURATED_BROADER | 0.78 |
| Recurrence | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Major hepatectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Major hepatectomy
- description
- Major hepatectomy was defined as the removal of four or more Couinaud's liver segments.
- interventionNames
- Procedure: Major hepatectomy
- label
- Minor hepatectomy
- description
- Minor hepatectomy was defined as the removal of three or fewer Couinaud's segments.
Primary outcomes (1)
- measure
- recurrence-free survival
- timeFrame
- 2019.1-2023.8
- description
- the time from the time of radical surgery to the time of HCC recurrence
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 85 Years
Show eligibility criteria text
Inclusion Criteria: * histologically confirmed solitary HCC with a size of ≥5 cm * Eastern Cooperative Oncology Group score of 0 or 1 * preoperative indocyanine green retention rate at 15 minutes ≤15% and Child-Pugh A classification * no evidence of vascular invasion or extrahepatic disease. Exclusion Criteria: * not diagnosed with HCC or had an HCC measuring \<5 cm * had confirmed tumor metastases or macrovascular invasion based on radiological examinations * died within 90 days after surgery were excluded
References
Publications (0)
Data not yet available
No reference posted for this study.