Clinical trial · Observational
Osteolysis of Allograft Prosthetic Composite After Shoulder Resection for Tumors
Results of Proximal Humeral Reconstruction With Allograft Prosthetic Composite After Resection for Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The gold standard after shoulder resection for tumors is reconstruction by reverse prosthesis and allograft. This is an intervention also performed for more frequent etiologies (revisions of prosthesis, non cancerous humeral bone loss ...). The results in these etiologies are good, and do not find any particular mechanical complications (including no osteolysis of the graft). In the case of reconstruction for cancer, the numbers of patients are lower (rare pathologies) and some studies on small numbers found osteolysis of the allograft. The aim of this study is to analyze the presence or not osteolysis in these patients, and to quantify it precisely by scanner measurement (no data yet in the literature).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Shoulder Disease | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| proximal humeral resection for tumor and allograft prosthetic composite reconstruction | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Osteolysis (bone stock in cm3)
- timeFrame
- within 3 months post operatively and up to 1 year post operatively
- description
- allograft bone stock by scanographic measurements after the surgery, and at minimum 6 month follow up
Secondary outcomes (3)
- measure
- Constant score
- timeFrame
- up to 1year post operatively
- description
- Shoulder functional evaluation score between 6 points (worst score) and 100 points (better score)
- measure
- Complications
- timeFrame
- up to 1year post operatively
- description
- (infection, dislocation)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * tumors of proximal humerus * Malawer type I resection * primary reconstruction by allograft prosthetic composite Exclusion Criteria: * resection and reconstruction by prosthesis alone * resection and reconstruction by prosthesis and cement sleeve reconstruction * resection and reconstruction by hemiarthroplasty * revision protheses.
References
Publications (0)
Data not yet available