Clinical trial · Interventional
Exercise Interventions for Improving Health in Breast Cancer Survivors
Comparing a Technology-enabled, Remotely Delivered Exercise Intervention to Partly-supervised Structured Exercise in Breast Cancer Survivors: a Randomised and Controlled Non- Inferiority Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Supervised, prescribed exercise has positive effects on body composition, physical functioning, psychological wellbeing and quality of life for patients after breast cancer treatment. However, exercise interventions are often time consuming, commonly take place at a health or fitness facility, and usually require a trained professional to be present. Cost-effective, enjoyable and practical approaches, that can be adopted at home or in local surroundings are needed. For example, an alternative approach is using an electronic physical activity tracking wristwatch to help patients engage with exercise or physical activity. Research demonstrates the importance of structured and supervised exercise for breast cancer survivors. However, it is not known whether other approaches (e.g. home-based exercise and physical activity) alongside the use of personalised technology-enabled feedback, can cause similar improvements to health when compared to structured exercise. The overall aim of this study is to determine whether cardiorespiratory fitness is changed by a technology enabled, remotely delivered exercise intervention and to determine whether this change is similar to the change caused by a partly supervised, prescribed exercise intervention. This study will also determine the influence of both interventions on physical functioning, body composition and blood pressure.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise intervention | Behavioral | — | UNRESOLVED |
| Polar A380 wristwatch physical activity tracker | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Partly supervised, prescribed exercise group
- description
- The partly-supervised, prescribed exercise group will be required to undertake two supervised exercise sessions and one unsupervised exercise session at home or in your local area each week. Supervised sessions will consist of exercising on both a treadmill and a stationary exercise bike. The intervention will be progressive, increasing in intensity and duration.
- interventionNames
- Behavioral: Exercise intervention
- type
- EXPERIMENTAL
- label
- Technology enabled, remotely delivered exercise group
- description
- The technology enabled, remotely delivered exercise group will receive information and advice about exercise that could be undertaken at home or in their local area. In addition, participants will received a Polar A370 fitness tracker wristwatch with heart rate monitoring chest strap. Participants will take part in exercise each week (most likely walking) which will increase in duration over 8-weeks from 105 minutes each week to 150 minutes each week. Each week a member of the research team will have a telephone call with the participant to discuss the exercise prescription.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 35 Years
- Maximum age
- 69 Years
Show eligibility criteria text
Inclusion Criteria: * Age 35-69 years * History of previous stage I-III invasive breast cancer * No history of metastatic cancer * No significant cardiac co-morbidity * No diagnosis of bilateral breast cancer * \> 2 months from surgery, chemotherapy and radiotherapy treatments, however patients continuing with endocrine therapy will be included. * BMI 20 \> \<35 kg.m2 * Oncologist clearance * Pass physical activity readiness questionnaire (PAR-Q) * Last menstrual period \>1 year ago Exclusion Criteria: * Current malignancy * Previous superficial basal cell carcinoma of the skin or prior carcinoma-in situ (including ductal carcinoma in situ/lobular carcinoma in situ of breast) is allowed * Cardiovascular Disease * Severe hypertension (\>200/120 mmHg) * 5+ years since last treatment * Active infection at recruitment * Undertaking regular, structured, exercise training defined as self-reported structured physical activity lasting \> 30 minutes on two or more occasions per week (measured before the first visit using the international physical activity questionnaire (IPAQ)) * Contraindication to undertaking an exercise programme including previously diagnosed significant osteoporosis or other co-morbidities at the oncologist's discretion
References
Publications (1)
- DERIVEDStruszczak L, Walhin JP, Betts J, Thompson D, Beresford M, Turner JE. Cardiorespiratory Fitness, Functional Fitness and Body Composition Among Breast Cancer Survivors With 8 Weeks of Exercise Training: A Randomised, Controlled Non-Inferiority Trial Comparing Remotely-Supported and Partly-Supervised Interventions. Cancer Med. 2026 Feb;15(2):e71608. doi: 10.1002/cam4.71608. PMID 41656158