Clinical trial · Observational
Functional Recovery of Patients Undergoing Resection and Reconstruction of the Lower Limbs for Bone Tumor.
Functional Recovery in the First Six Postoperative Months of Cancer Patients Undergoing Lower Limb Resection and Reconstruction. An Observational Study
NCT06376539CI-TRIAL-00102300FISIO-ONCOcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of the present study is to describe the course of functional recovery of patients with musculoskeletal tumours and undergone resection and reconstruction operations of lower limbs in the first six months post-surgery, differentiating them on the basis of the anatomical level involved.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Bone Neoplasm | Bone Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Rehabilitation | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (2)
- measure
- Toronto Extremity Salvage Score (TESS)
- timeFrame
- at 3 months after surgery
- description
- Person's level of independence. It is measured through 30 questions relating to 30 activities of daily living to be answered by the patient. The total score is reported from 0 to 100. A higher score indicates a greater degree of autonomy. A higher score indicates a greater degree of autonomy.
- measure
- Toronto Extremity Salvage Score (TESS)
- timeFrame
- at 6 months after surgery
- description
- Person's level of independence. It is measured through 30 questions relating to 30 activities of daily living to be answered by the patient. The total score is reported from 0 to 100. A higher score indicates a greater degree of autonomy. A higher score indicates a greater degree of autonomy.
Secondary outcomes (8)
- measure
- Range of motion (ROM)
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 12 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * All participants undergone lower limb resection and reconstruction with localisation of the disease to the pelvis, femur femur, tibia and foot bones. * All participants undergone soft tissue resection surgery on the of the lower limb * All types of oncological diagnoses will be taken considered: osteosarcoma, Ewing and others. Exclusion Criteria: * Participants who undergo at our Institute only the surgical treatment while continuing adjuvant treatment at other centres * Participants for whom no rehabilitation treatment has been activated during adjuvant treatment at our Institute
References
Publications (1)
- DERIVEDMorri M, Venturini E, Abbruzzese A, Meneghini M, Raffa D, Berti L, Donati D. The functional recovery trajectory in patients undergoing lower limb salvage surgery for bone tumour: an observational study. Support Care Cancer. 2026 Jan 28;34(2):136. doi: 10.1007/s00520-026-10374-x. PMID 41593389