Clinical trial · Observational
A Multicentre Real-world Study of Heptapopal Ethanolamine Tablets in Concurrent/Sequential Radioimmunoinduced Thrombocytopenia
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The objective of this study was to observe and evaluate the efficacy and safety of hexapopal ethanolamine tablets in the treatment of synchronous/sequential radioimmunoinduced thrombocytopenia in the real world. The subjects of this study were patients with solid malignant tumors who had received radioimmunoinduced thrombocytopenia. This study will retrospectively and prospectively collect real-world data related to investigational drugs, and will observe 500 patients to observe the diagnosis and treatment pattern of radiochemo-induced thrombocytopenia. The study included a screening period (no more than one week) and a treatment period (at least two cycles).Participants meeting protocol inclusion criteria were defined as having platelet values \< 100×109/L during radioimmunotherapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer, Therapy-Related | Therapy-Related Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Herombopag Olamine Tablets | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Single drug group
- interventionNames
- Drug: Herombopag Olamine Tablets
- label
- combined rhTPO group
- interventionNames
- Drug: Herombopag Olamine Tablets
- label
- combined IL-11 group
- interventionNames
- Drug: Herombopag Olamine Tablets
Primary outcomes (1)
- measure
- The proportion of patients recovered to 100×109/L
- timeFrame
- 14 days after starting treatment with the study drug
- description
- The proportion of patients who recovered to 100×109/L within 14 days after starting treatment with the drug was studied
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Understand the research procedure and voluntarily sign the informed consent to participate in the study * Subjects ≥18 years of age receiving synchronous/sequential chemotherapeutic therapy * Patients with platelet count ≤100×109/L or platelet count decrease ≥ 50×109/L or platelet count \> 100×109/L but need to be prophylaxis with hexapopethanolamine tablets * Researchers believe that subjects need to be treated with hexapopal. Exclusion Criteria: * The subjects are conducting clinical intervention studies * Patients with known or expected allergy or intolerance to the active ingredient or excipient of hexapopar * Pregnant or lactating women * Other conditions deemed unsuitable for inclusion in the study by the researcher.
References
Publications (0)
Data not yet available