Clinical trial · Observational
Dietary Factors Associated to Colorectal Premalignant Lesions (COLOMAR-1)
NCT06368661CI-TRIAL-00079248unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study aims to find a correlation between fish protein intake and other dietary habits and colorectal premalignant lesions in healthy volunteers. It also aims to describe gut microbial profiles for each dietary pattern, in order to elucidate the role of fish intake in cancer prevention.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Nutrition Related Neoplasm/Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Dietary habits registry from participants: the dietary intake
- timeFrame
- Dietary habits will be taken by an online specific Food Frequency Questionnaire (FFQ) for Spanish population. The data analysis will be taken at baseline outcome. 3 months
- description
- Dietary habits will be taken by an online specific Food Frequency Questionnaire (FFQ) for Spanish population. The data analysis will be taken at baseline outcome.
- measure
- Biomarkers in colon mucosa, precancerous lesions and colorectal cancer
- timeFrame
- 3 months
- description
- Alkylating signature will be determined in normal mucosa of right and left colon, premalignant lesions and colorectal cancer
- measure
- Gut microbiota profile
- timeFrame
- 4 months
- description
- Differences in profile of gut microbiota among participants with and without precancerous lesions and colorectal cancer will be evaluated. Differences in profile of gut microbiota among different profiles of dietary habits will be evaluated.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 45 Years
Show eligibility criteria text
Inclusion Criteria: * 45 years old or more. * Be willing to participate in the study. Exclusion Criteria: * Pregnancy * Previous colorectal cancer. * Familial colorectal cancer syndrome. * Previous colonoscopy and colon polypectomy (last five years ). * Inflammatory bowel disease. * Medical contraindication for colonoscopy at investigator´s criteria.
References
Publications (0)
Data not yet available
No reference posted for this study.