Clinical trial · Interventional
Conversational Agents to Improve HPV Vaccine Acceptance in Primary Care (ECA-HPV)- Clinical Trial
Conversational Agents to Improve HPV Vaccine Acceptance in Primary Care
NCT06367699CI-TRIAL-00092151terminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): We were informed by the NCI that this research no longer aligns with NCI values, therefore our grant was terminated and we had received a stop work order.
Summary
Brief summary (as posted)
The objective of this study is to assess the use of and satisfaction with the ECA-HPV intervention over a 16-month period, its ability to increase HPV vaccination, and the comparative effectiveness of clinic notification and adolescent ECA components on these factors.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Human Papilloma Virus | — | UNRESOLVED | — |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ECA-HPV App with Adolescent Function Enabled | Behavioral | — | UNRESOLVED |
| ECA-HPV App with Clinic Notification and Adolescent Functions Disabled | Behavioral | — | UNRESOLVED |
| ECA-HPV App with Clinic Notification and Adolescent Functions Enabled | Behavioral | — | UNRESOLVED |
| ECA-HPV App with Clinic Notification Function Enabled | Behavioral | — | UNRESOLVED |
| Usual Care | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (5)
- type
- ACTIVE_COMPARATOR
- label
- Usual Care
- description
- An internet-based measure, REDCap, will be used for parent/guardian and adolescent participants to complete surveys at baseline, after the index well child visit, and after the second well child visit. Both parent/guardian and adolescent participants do not have access to the ECA-HPV app. Adolescent participants will receive usual standard of care.
- interventionNames
- Behavioral: Usual Care
- type
- EXPERIMENTAL
- label
- ECA-HPV App with Clinic Notification and Adolescent Functions Disabled
- description
- The ECA-HPV (Embodied Conversational Agent adapted for this project) system comprises of a smartphone-based ECA parent/guardian interface, where the parent/guardian participants can receive HPV vaccine promotion and counseling from an interactive agent. The clinic notification feature is disabled on the app. Adolescent participants do not receive the adolescent version of the ECA-HPV app. An internet-based measure, REDCap, will be used for parent/guardian and adolescent participants to complete surveys at baseline, after the index well child visit, and after the second well child visit.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 8 Years
- Maximum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: For parent/guardian participants: 1. Speaks English fluently 2. Able to independently consent 3. Has adequate corrected vision to use the ECA-HPV system (based on their ability to go through the consent form) 4. Has adequate hearing to use the ECA-HPV system (based on their ability to hear the research staff member conducting the consent process) 5. Has a smartphone that is able to support the ECA-HPV app For adolescent participants: 1. Is between the ages of 9-12 at the time of the index (first) well child visit 2. Has received either 1 or none of the HPV vaccine series 3. Speaks English fluently 4. Able to independently assent 5. Has adequate corrected vision to use the ECA-HPV system 6. Has adequate hearing to use the ECA-HPV system 7. Has a smartphone or has access to parent/guardian's smartphone (that is able to support the ECA-HPV app) 8. Has an upcoming well child visit at Boston Medical Center Exclusion Criteria (for all participants): 1. Is not able to use the ECA-HPV system 2. Has already participated in the study before
References
Publications (0)
Data not yet available
No reference posted for this study.