Clinical trial · Observational
Differential Expression and Potential Value of c-MYC in Non-Invasive and Invasive Mammary Carcinoma
Differential Expression and Potential Value of c-MYC in Non-invasive and Invasive Mammary Carcinoma
NCT06357338CI-TRIAL-00075890unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Invasive Breast Cancer | Invasive Breast Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| no intervention | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- non invasive mammary carcinoma
- description
- 35 cases with non invasive breast cancer with low and high nuclear grades and co existing microfoci of invasion
- interventionNames
- Other: no intervention
- label
- invasive mammary carcinoma
- description
- 35 cases of invasive breast cancer undergone MRM and classify them according grading, staging and luminal subtypes
- interventionNames
- Other: no intervention
Primary outcomes (1)
- measure
- role of c-MYC in breast cancer
- timeFrame
- 1 year
- description
- difference between expression of c-MYC in non invasive and invasive mammary carcinoma
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 15 Years
Show eligibility criteria text
Inclusion Criteria: Specimens of Modified Radical Mastectomies from breast carcinoma patients Exclusion Criteria: * Cases with insufficient clinical data. * Tissue blocks of destroyed or insufficient material, unfit for diagnosis. * Cases who received pre-operative chemotherapy.
References
Publications (1)
- BACKGROUNDGao FY, Li XT, Xu K, Wang RT, Guan XX. c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment. Cell Commun Signal. 2023 Jan 31;21(1):28. doi: 10.1186/s12964-023-01043-1. PMID 36721232