Clinical trial · Observational
BEST-RPP Pilot: Screening for Esophageal Cancer in Rural Oregon Without an Endoscopy
Barrett's Esophagus Screening Towards Rural Referral Pathways: Screening for Esophageal Cancer in Rural Oregon Without Endoscopy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Recent advancements in swallowable esophageal cell-collection devices (SECD) offer a safe, minimally invasive, accurate, and low-cost alternative to esophageal screening without the need for an upper endoscopy. The BEST-RPP study aims to evaluate the acceptability and feasibility of using this novel approach to screen for Barrett's Esophagus (BE) and Esophageal Carcinoma (EAC) in rural primary care clinic settings in Oregon.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Esophageal Cancer | Malignant Esophageal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Screening with swallowable esophageal cell-collection devices (SECD) | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients with suspected Barrett's Esophagus or at risk for esophageal cancer
- description
- Patients who receive primary care in a rural settings and are in need of screening for Barrett's Esophagus or esophageal cancer.
- interventionNames
- Device: Screening with swallowable esophageal cell-collection devices (SECD)
Primary outcomes (7)
- measure
- Feasibility of the use of a SECD: Number of providers who indicate likelihood of using SECD
- timeFrame
- 8 months
- description
- Feasibility of screening for esophageal cancer via SECD in rural primary care settings will be measured by data collected from Provider Post-Inservice Questionnaire, which includes, Indication of provider likelihood of using SECD as a screening tool.
- measure
- Feasibility of the use of SECD: Number of providers who indicate willingness to be trained and train clinic staff
- timeFrame
- 8 months
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * Signed informed consent * Willing and able to comply with the protocol * Live in a rural area * Chronic GERD Dx * 3 or more of the following risk factors: Male, age \>50 years White race Tobacco smoking Obesity Family history of BE or EAC in a first-degree relative Exclusion Criteria: \-
References
Publications (0)
Data not yet available